Evidence map›Paper›PMID 29697758›Full record

ReviewThe journals of gerontology. Series A, Biological sciences and medical sciences2019

Pathways, Contributors, and Correlates of Functional Limitation Across Specialties: Workshop Summary.

Stephen B Kritchevsky, Daniel E Forman, Kathryn E Callahan, E Wesley Ely, Kevin P High, Frances McFarland, Eliseo J Pérez-Stable, Kenneth E Schmader, Stephanie A Studenski, John Williams and 2 more

Open access · bronzeAbstract readReview
In one paragraph

Review in The journals of gerontology. Series A, Biological sciences and medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Multidimensional functional limitations in American cancer survivors: Characteristics and their effects on survival and healthcare utilization.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Article
  5. Article
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  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Use of Functional Assessment to Define Therapeutic Goals and Treatment.Journal of the American Geriatrics Society · 2019
    Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Stephen B KritchevskyDepartment of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Daniel E FormanDepartment of Medicine, University of Pittsburgh, Pennsylvania.
Kathryn E CallahanDepartment of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.
E Wesley ElyVA Tennessee Valley Geriatric Research Education Clinical Center (GRECC) and Department of Medicine, Vanderbilt University, Nashville.
Kevin P HighDepartment of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Frances McFarlandDepartment of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Eliseo J Pérez-StableNational Institute on Minority Health and Health Disparities, Bethesda, Maryland.
Kenneth E SchmaderDurham VA GRECC and Duke University Medical Center, North Carolina.
Stephanie A StudenskiNational Institute on Aging, Bethesda, Maryland.
John WilliamsNational Institute on Aging, Bethesda, Maryland.
Susan ZiemanNational Institute on Aging, Bethesda, Maryland.
Jack M GuralnikDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore.
Wake Forest University · USNational Institute on Aging · USGeriatric Research Education and Clinical Center · USNational Institute on Minority Health and Health Disparities · USUniversity of Maryland, Baltimore · USUniversity of Pittsburgh · US

Funding

Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Denise Kathryn Houston · 2002 to 2026
$36.4M
Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI Sarah B. Peskoe · 2006 to 2026
$24.6M
A Transdisciplinary Approach to Engage Specialty Investigators in Aging ResearchU13AG040938 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HIGH, KEVIN P., KRITCHEVSKY, STEPHEN B. · 2011 to 2019
$423k
NIA NIH HHS P30 AG021332NIA NIH HHS P30 AG028716NIA NIH HHS U13 AG040938
6 · The paper itself

Abstract

Traditional clinical care models focus on the measurement and normalization of individual organ systems and de-emphasize aspects of health related to the integration of physiologic systems. Measures of physical, cognitive and sensory, and psychosocial or emotional function predict important health outcomes like death and disability independently from the severity of a specific disease, cumulative co-morbidity, or disease severity measures. A growing number of clinical scientists in several subspecialties are exploring the utility of functional assessment to predict complication risk, indicate stress resistance, inform disease screening approaches and risk factor interpretation, and evaluate care. Because a substantial number of older adults in the community have some form of functional limitation, integrating functional assessment into clinical medicine could have a large impact. Although interest in functional implications for health and disease management is growing, the science underlying functional capacity, functional limitation, physical frailty, and functional metrics is often siloed among different clinicians and researchers, with fragmented concepts and methods. On August 25-26, 2016, participants at a trans-disciplinary workshop, supported by the National Institute on Aging and the John A. Hartford Foundation, explored what is known about the pathways, contributors, and correlates of physical, cognitive, and sensory functional measures across conditions and disease states; considered social determinants and health disparities; identified knowledge gaps, and suggested priorities for future research. This article summarizes those discussions.

Indexed as

AgingMobility LimitationFrailtyHumansCognitionDisabilityFrailtyPhysical performance

Identifiers

PMID29697758
PMCPMC6417483
OpenAlexW2801848059

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.