Trial reportArthritis care & research2019
Effects of Aerobic and Resistance Exercise in Older Adults With Rheumatoid Arthritis: A Randomized Controlled Trial.
Trial report in Arthritis care & research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 3 syntheses or guidelines pooled it, 97 citations in OpenAlex.
- Effects of interventions with resistance exercises on muscle strength, physical disability, and quality of life in systemic sclerosis patients: a systematic review with meta-analysis.Advances in rheumatology (London, England) · 2025Pooled it
- Impact of physical exercise interventions on functional fitness in older adults.Frontiers in medicine · 2025Pooled it
- A systematic review exploring the evidence reported to underpin exercise dose in clinical trials of rheumatoid arthritis.Rheumatology (Oxford, England) · 2020Pooled it
- Effectiveness of Yoga and Combined Exercise in Female With Rheumatoid Arthritis: Randomized Controlled Trial.Musculoskeletal care · 2026Trial
- Effects of tumour necrosis factor and interleukin-6 inhibitor therapy on exercise-related visceral adipose tissue reduction in rheumatoid arthritis.Experimental physiology · 2026Trial
- Trial
- High-intensity exercise improves multidimensional fatigue and health-related quality of life in rheumatoid arthritis: a randomized controlled study.Arthritis research & therapy · 2025Trial
- High-intensity interval training improves cardiovascular and physical health in patients with rheumatoid arthritis: a multicentre randomised controlled trial.British journal of sports medicine · 2024Trial
- Trial
- Moderate-to-high intensity exercise with person-centered guidance influences fatigue in older adults with rheumatoid arthritis.Rheumatology international · 2019Trial
- Article
- Improving Psychological Well-Being and Quality of Life in Rheumatoid Arthritis-Associated Interstitial Lung Disease Through Exercise and Pulmonary Rehabilitation: A Narrative Review.Healthcare (Basel, Switzerland) · 2026Review
- Effect of Physical Therapy with Combined Resistance Exercises and Vigorous Walking in Older Adult Women with Chronic Non-Specific Pain: A Randomized Controlled Trial.Life (Basel, Switzerland) · 2026Article
- Interpretable framework for predicting preoperative cardiorespiratory fitness using wearable data.Computer methods and programs in biomedicine · 2025Article
- Advancements in mesenchymal stromal cells for treating connective tissue disease-associated interstitial lung disease: from basic research to clinical application.Stem cell research & therapy · 2025Review
- Physical activity of older patients with rheumatoid arthritis.Rheumatology international · 2025Review
- IL-6 Inhibitors and TNF Inhibitors: Impact on Exercise-induced Cardiac Adaptations in Patients With Rheumatoid Arthritis.JACC. Basic to translational science · 2025Article
- Eccentric Exercise Guidelines for Managing Rheumatoid Arthritis: Findings From a Randomized Controlled Trial.Health science reports · 2025Article
- Individual cardiorespiratory fitness exercise prescription for older adults based on a back-propagation neural network.Frontiers in public health · 2025Article
- Synergistic effect of Majoon-e-Suranjaan and isometric exercises in improving rheumatoid arthritis.American journal of translational research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo evaluate the effect of a moderate-to-high-intensity, aerobic and resistance exercise with person-centered guidance in older adults with rheumatoid arthritis (RA), through a randomized controlled multicenter trial.
methodsOlder adults (ages 65-75 years) with RA (n = 74) were randomized to either a 20-week exercise intervention at a gym (n = 36) or to home-based exercise of light intensity (n = 38). Assessments were performed at baseline, at 20 weeks, and at 12 months. The primary outcome was the difference in the Health Assessment Questionnaire disability index (HAQ DI) score, and the secondary outcomes were the differences in physical fitness assessed by a cardiopulmonary exercise test, an endurance test, the timed up and go test, the sit to stand test, and an isometric elbow flexion force measurement.
resultsNo significant differences between the groups were found for the primary outcome, HAQ DI score. Within the intervention group there was a significant improvement in the HAQ DI score when compared to baseline (P = 0.022). Aerobic capacity (P < 0.001) and 3 of 4 additional performance-based tests of endurance and strength significantly improved (P < 0.05) in the intervention group when compared to the control group. In the intervention group, 71% of patients rated their health as much or very much improved compared to 24% of patients in the control group (P < 0.001). At the 12-month follow-up, there were no significant differences in change between the 2 groups on the HAQ DI score. A significant between-group difference was found for change in an endurance test (P = 0.022).
conclusionAerobic and resistance exercise with person-centered guidance improved physical fitness in terms of aerobic capacity, endurance, and strength in older adults with RA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.