Evidence map›Paper›PMID 29696752›Full record

ArticleJournal of applied clinical medical physics2018

Clinical implementation of AXB from AAA for breast: Plan quality and subvolume analysis.

Alexandra Guebert, Leigh Conroy, Sarah Weppler, Majed Alghamdi, Jessica Conway, Lindsay Harper, Tien Phan, Ivo A Olivotto, Wendy L Smith, Sarah Quirk

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Impact of acuros XB algorithm in deep-inspiration breath-hold (DIBH) respiratory techniques used for the treatment of left breast cancer.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alexandra GuebertDepartment of Physics and Astronomy, University of Calgary, Calgary, AB, Canada.
Leigh ConroyDepartment of Physics and Astronomy, University of Calgary, Calgary, AB, Canada.
Sarah WepplerDepartment of Physics and Astronomy, University of Calgary, Calgary, AB, Canada.
Majed AlghamdiDivision of Radiation Oncology, Department of Oncology, University of Calgary, Calgary, AB, Canada.
Jessica ConwayDivision of Radiation Oncology, Department of Oncology, University of Calgary, Calgary, AB, Canada.
Lindsay HarperDepartment of Oncology, Tom Baker Cancer Centre, Calgary, AB, Canada.
Tien PhanDivision of Radiation Oncology, Department of Oncology, University of Calgary, Calgary, AB, Canada.
Ivo A OlivottoDivision of Radiation Oncology, Department of Oncology, University of Calgary, Calgary, AB, Canada.
Wendy L SmithDepartment of Physics and Astronomy, University of Calgary, Calgary, AB, Canada.
Sarah QuirkDepartment of Physics and Astronomy, University of Calgary, Calgary, AB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTwo dose calculation algorithms are available in Varian Eclipse software: Anisotropic Analytical Algorithm (AAA) and Acuros External Beam (AXB). Many Varian Eclipse-based centers have access to AXB; however, a thorough understanding of how it will affect plan characteristics and, subsequently, clinical practice is necessary prior to implementation. We characterized the difference in breast plan quality between AXB and AAA for dissemination to clinicians during implementation.

methodsLocoregional irradiation plans were created with AAA for 30 breast cancer patients with a prescription dose of 50 Gy to the breast and 45 Gy to the regional node, in 25 fractions. The internal mammary chain (IMC

resultsThere were minimal differences found between the AXB and AAA calculated plans. The median difference between AXB and AAA for breast

conclusionWe observed minimal difference in magnitude and spatial distribution of dose when comparing the two algorithms. The largest observable differences occurred in superficial dose regions. Therefore, clinical implementation of AXB from AAA for breast radiotherapy is not expected to result in changes in clinical practice for prescribing or planning breast radiotherapy.

Indexed as

AlgorithmsAnisotropyBreast NeoplasmsFemaleHumansOrgans at RiskQuality Assurance, Health CareRadiometryRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedAcurosbreastclinical implementationdose calculation algorithms

Identifiers

PMID29696752
PMCPMC5978944

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.