ArticleClinical cardiology2018
Atrial fibrillation patient preferences for oral anticoagulation and stroke knowledge: Results of a conjoint analysis.
Article in Clinical cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- The Evolving Landscape of Discrete Choice Experiments in Health Economics: A Systematic Review.PharmacoEconomics · 2025Pooled it
- Pooled it
- Effect of Integrated Care on Patients With Atrial Fibrillation: A Systematic Review of Randomized Controlled Trials.Frontiers in cardiovascular medicine · 2022Pooled it
- Effects of anticoagulation in patients with device-detected atrial fibrillation and multiple stroke risk factors: a win ratio analysis of the NOAH-AFNET 6 trial.European heart journal. Quality of care & clinical outcomes · 2025Trial
- Patients and Their Physician's Perspectives About Oral Anticoagulation in Patients With Atrial Fibrillation Not Receiving an Anticoagulant.JAMA network open · 2023Trial
- Influence of a COVID-19 vaccine's effectiveness and safety profile on vaccination acceptance.Proceedings of the National Academy of Sciences of the United States of America · 2021Trial
- Comparison of Rating Scale, Time Tradeoff, and Conjoint Analysis Methods for Assessment of Preferences in Prostate Cancer.Medical decision making : an international journal of the Society for Medical Decision Making · 2019Trial
- Patient Preference Phenotypes for Post-operative Anticoagulation After Hip or Knee Replacement: A Cross-sectional Survey Study.Journal of general internal medicine · 2026Article
- Post-operative anticoagulation therapy after knee or hip replacement: The role of patients' preferences in selection of therapy.Research square · 2025Article
- Facilitating active participation in anticoagulant decisions in advanced kidney disease: co-production of a question prompt list.BMC nephrology · 2025Article
- Physician and Patient Preferences for Oral Anticoagulation Therapy Decision Making in Atrial Fibrillation: Results From a National Best-Worst Scaling Survey in Türkiye.Clinical cardiology · 2024Article
- Left Ventricular Thrombus After Myocardial Infarction: Opinions and Equipoise.Cardiovascular drugs and therapy · 2024Article
- Assessment and mitigation of bleeding risk in atrial fibrillation and venous thromboembolism: A Position Paper from the ESC Working Group on Thrombosis, in collaboration with the European Heart Rhythm Association, the Association for Acute CardioVascular Care and the Asia-Pacific Heart Rhythm Society.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2022Article
- 2021 European Heart Rhythm Association Practical Guide on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2021Article
- World Heart Federation Roadmap on Atrial Fibrillation - A 2020 Update.Global heart · 2021Review
- Understanding the barriers to using oral anticoagulants among long-term aspirin users with atrial fibrillation - a qualitative study.BMC health services research · 2020Article
- Patient perception of anticoagulant treatment for stroke prevention (RE-SONANCE study).Open heart · 2020Observational
- An Analysis of Perceived and Actual Anticoagulant Knowledge among Independent Pharmacy Patients.Innovations in pharmacy · 2020Article
- Mind the gap: Deficits in fundamental disease-specific knowledge in atrial fibrillation.International journal of cardiology · 2019Article
- Treatment Expectations, Convenience, and Satisfaction with Anticoagulant Treatment: Perceptions of Patients in South-East Queensland, Australia.Journal of clinical medicine · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGuidelines recommend that patients with atrial fibrillation (AF) are involved in oral anticoagulant (OAC) treatment decisions. Understanding which OAC attributes AF patients value most could help optimize treatment.
objectiveTo assess the relationship between patient's stroke knowledge and their preferences for specific OAC attributes.
methodsA cross-sectional online survey was conducted in patients with nonvalvular AF taking an OAC for stroke prevention in the United States, Canada, Germany, France, and Japan. Patients were asked about their stroke knowledge, perception of the seriousness of AF and concern about stroke, and to rank 7 OAC attributes in order of importance. A conjoint analysis was performed to determine the inherent value of 4 attributes.
resultsIn total, 937 patients (mean age [standard deviation] 54.3 [16.6] years; 37.1% female) participated. Of these, 19.5%, 27.9%, and 29.8% had good, moderate, and low stroke knowledge, respectively; 22.8% had no stroke knowledge. Overall, 39.4% of patients (47.5% with good stroke knowledge) perceived AF as very/extremely serious. The OAC attribute ranked as most important was stroke prevention followed by major bleeding risk, other side effects, dosing frequency, antidote availability, dietary restrictions, and use with/without food. In the conjoint analysis, stroke risk reduction was the most valued property, followed by reduction in major bleeding risk, less frequent administration, and administration with/without food. Preferences did not differ with level of stroke knowledge, perception of seriousness of AF, concern of stroke, or medication burden.
conclusionsMost AF patients consider efficacy and safety to be the most important OAC attributes, whereas dosing frequency was deemed as less important.
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