Evidence map›Paper›PMID 29696523›Full record

ArticleMycotoxin research2018

Occurrence of ochratoxin A in Astragalus propinquus root and its transfer to decoction.

Jakub Toman, Vladimir Ostry, Yann Grosse, Tomas Roubal, Frantisek Malir

Abstract read
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In one paragraph

Article in Mycotoxin research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 4 countries.

Jakub TomanFaculty of Science, Department of Biology, University of Hradec Kralove, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic. jakub.toman.1@uhk.cz.ORCID http://orcid.org/0000-0002-7396-5503
Vladimir OstryFaculty of Science, Department of Biology, University of Hradec Kralove, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic.
Yann GrosseInternational Agency for Research on Cancer, 150 Cours Albert Thomas, 69372, Lyon Cedex, France.
Tomas RoubalInstitute of Public Health in Usti nad Labem, Regional Branch Hradec Kralove, Nezvalova 958, 500 03, Hradec Kralove, Czech Republic.
Frantisek MalirFaculty of Science, Department of Biology, University of Hradec Kralove, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic.
University of Hradec Králové · CZCentre international de recherche sur le cancer · FRNational Institute of Public Health · SI

Funding

World Health Organization 001
6 · The paper itself

Abstract

The aim of this study was to conduct a survey assessing (a) the ochratoxin A (OTA) content in different samples of Astragalus propinquus root (AR), one of the fundamental herbs in traditional Chinese medicine, and (b) the rate of OTA transfer to AR decoctions that are traditionally used to reduce general weakness and increase overall vitality. A validated method of high-performance liquid chromatography with fluorescence detection (HPLC-FLD) was used to determine OTA concentrations in AR samples and AR decoctions. The limit of quantification was 0.35 ng/g; the recovery of the HPLC method for AR samples was 82%; and the relative standard deviation (SD) of repeatability was 2.6%. All 40 tested AR samples were positive, with a mean value of 451.0 ng/g (range, 28.8-1700.0 ng/g). The transfer rate of OTA to decoctions, from a naturally contaminated and homogenized AR sample (internal reference material) with a concentration of OTA of 288.9 ng/g ± 12.3 (SD), was 83.4% ± 8.5 (SD). We believe it is necessary to continue OTA monitoring in AR and other herbal products, estimate the actual human usual intake, and perform health risk assessment.

Indexed as

Astragalus propinquusChromatography, High Pressure LiquidDrugs, Chinese HerbalFluorometryFood ContaminationHumansOchratoxinsDrugs, Chinese HerbalHuang Qiochratoxin AOchratoxinsAstragalus propinquus SchischkinHerbal food supplementHerbal productsHPLC-FLDOchratoxin ATraditional Chinese medicine

Identifiers

PMID29696523
OpenAlexW2802293858

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.