Evidence map›Paper›PMID 29696435›Full record

ArticleJournal of abnormal child psychology2019

Parenting Interacts with Oxytocin Polymorphisms to Predict Adolescent Social Anxiety Symptom Development: A Novel Polygenic Approach.

Stefanie A Nelemans, Evelien van Assche, Patricia Bijttebier, Hilde Colpin, Karla van Leeuwen, Karine Verschueren, Stephan Claes, Wim van den Noortgate, Luc Goossens

Open access · hybridAbstract read
In one paragraph

Article in Journal of abnormal child psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 23 citations in OpenAlex.

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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Stefanie A NelemansResearch Unit School Psychology and Development in Context, KU Leuven, Leuven, Belgium. s.a.nelemans@uu.nl.
Evelien van AsscheGRASP-Research Group, Department of Neuroscience, KU Leuven, Leuven, Belgium.
Patricia BijttebierResearch Unit School Psychology and Development in Context, KU Leuven, Leuven, Belgium.
Hilde ColpinResearch Unit School Psychology and Development in Context, KU Leuven, Leuven, Belgium.
Karla van LeeuwenParenting and Special Education Research Group, KU Leuven, Leuven, Belgium.
Karine VerschuerenResearch Unit School Psychology and Development in Context, KU Leuven, Leuven, Belgium.
Stephan ClaesGRASP-Research Group, Department of Neuroscience, KU Leuven, Leuven, Belgium.
Wim van den NoortgateMethodology of Educational Sciences Research Group, KU Leuven, Leuven, Belgium.
Luc GoossensResearch Unit School Psychology and Development in Context, KU Leuven, Leuven, Belgium.
KU Leuven · BE

Funding

Onderzoeksraad, KU Leuven GOA/12/009Onderzoeksraad, KU Leuven PDM/15/085
6 · The paper itself

Abstract

Guided by a developmental psychopathology framework, research has increasingly focused on the interplay of genetics and environment as a predictor of different forms of psychopathology, including social anxiety. In these efforts, the polygenic nature of complex phenotypes such as social anxiety is increasingly recognized, but studies applying polygenic approaches are still scarce. In this study, we applied Principal Covariates Regression as a novel approach to creating polygenic components for the oxytocin system, which has recently been put forward as particularly relevant to social anxiety. Participants were 978 adolescents (49.4% girls; M

Indexed as

Gene-Environment InteractionParent-Child RelationsParentingAdolescentAnxietyFemaleHumansLongitudinal StudiesMaleMultifactorial InheritanceOxytocinPersonal AutonomyPhobia, SocialPolymorphism, Single NucleotideOxytocinAdolescenceGene-by-environment interaction analysis (G × E)Longitudinal studyOxytocinParentingPolygenic scoresSocial anxiety symptoms

Identifiers

PMID29696435
PMCPMC6599763
OpenAlexW2800123298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.