ArticleEuropean radiology2018
Subtraction CT angiography improves evaluation of significant coronary artery disease in patients with severe calcifications or stents-the C-Sub 320 multicenter trial.
Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Understanding Photon-Counting CT: Physics, Detector Technology, and Image Reconstructions.Sensors (Basel, Switzerland) · 2026Review
- Diagnostic value of subtraction CT in evaluating the efficacy of transcatheter arterial chemoembolization-treated hepatocellular carcinoma patients compared to conventional CT and MRI.Quantitative imaging in medicine and surgery · 2026Article
- Diagnostic value of deep learning reconstruction-based subtraction CT-FFR in patients with calcified-related stenosis or stent implantation.Quantitative imaging in medicine and surgery · 2025Article
- A calcification subtraction method for postmortem coronary computed tomography angiography.International journal of legal medicine · 2025Article
- Article
- [Assessment of Coronary Stenosis Using Coronary CT Angiography in Patients with High Calcium Scores: Current Limitations and Future Perspectives].Journal of the Korean Society of Radiology · 2024Review
- Cardiac CT blooming artifacts: clinical significance, root causes and potential solutions.Visual computing for industry, biomedicine, and art · 2022Review
- Diagnostic Accuracy of Subtraction Coronary CT Angiography in Severely Calcified Segments: Comparison Between Readers With Different Levels of Experience.Frontiers in cardiovascular medicine · 2022Article
- Incremental Diagnostic Value of CT Fractional Flow Reserve Using Subtraction Method in Patients with Severe Calcification: A Pilot Study.Journal of clinical medicine · 2021Article
- Incremental improvement of diagnostic performance of coronary CT angiography for the assessment of coronary stenosis in the presence of calcium using a dual-layer spectral detector CT: validation by invasive coronary angiography.The international journal of cardiovascular imaging · 2021Article
- Feasibility of Subtraction Coronary Computed Tomographic Angiography and Influencing Factor Analysis: a Retrospective Study.Current medical science · 2021Article
- Subtraction improves the accuracy of coronary CT angiography for detecting obstructive disease in severely calcified segments.European radiology · 2021Article
- Advances in CT Techniques in Vascular Calcification.Frontiers in cardiovascular medicine · 2021Review
- Diagnostic Improvements of Deep Learning-Based Image Reconstruction for Assessing Calcification-Related Obstructive Coronary Artery Disease.Frontiers in cardiovascular medicine · 2021Article
- Clinical Applications of Wide-Detector CT Scanners for Cardiothoracic Imaging: An Update.Korean journal of radiology · 2019Review
- Modified Subtraction Coronary CT Angiography with a Two-Breathhold Technique: Image Quality and Diagnostic Accuracy in Patients with Coronary Calcifications.Korean journal of radiology · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
objectivesDiagnostic accuracy of conventional coronary CT angiography (CCTA
methodsIn this study, 180 symptomatic patients scheduled for invasive coronary angiography (ICA) were prospectively enrolled and CT scanned (2013-2016) at three international centers. CCTA
resultsAfter exclusion of 76 patients, 104 (14% females) with mean age 67 years and median Agatston score 852 were included. There were 136 target segments with misregistration and 121 target segments without. Accuracy calculations in target segments without misregistration showed a reduction of the false positives from 72% [95% confidence interval (CI): 63-80%] in CCTA
conclusionsIn severely calcified coronary arteries or stents, CCTA KEY POINTS: • A high calcium-score reduces the diagnostic accuracy in patients scanned with cardiac CT. • These patients would normally need an invasive angiogram for diagnosis. • In this prospective, multicenter study, subtraction CT, when evaluable, reduces false-positive stenosis evaluations. • Subtraction coronary CT angiography may, when evaluable, reduce excessive downstream testing.
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