Evidence map›Paper›PMID 29696404›Full record

ArticleAIDS and behavior2018

Mother-to-Child Transmission of HIV and HIV-Free Survival in Swaziland: A Community-Based Household Survey.

Caspian Chouraya, Rhoderick Machekano, Simangele Mthethwa, Krysia Lindan, Munamato Mirira, Kwashie Kudiabor, Michelle M Gill, Gugu Maphalala, Godfrey Woelk, Laura Guay

Abstract read
In one paragraph

Article in AIDS and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Caspian ChourayaElizabeth Glaser Pediatric AIDS Foundation, MVA Office Park, Corner of Mbhilibhi and Tsekwane Streets, P.O. Box A507, Mbabane, H100, Swaziland. cchouraya@pedaids.org.ORCID http://orcid.org/0000-0002-2325-1449
Rhoderick MachekanoElizabeth Glaser Pediatric AIDS Foundation, Washington, DC, USA.
Simangele MthethwaSexual Reproductive Health Unit, Ministry of Health, Mbabane, Swaziland.
Krysia LindanDepartment of Epidemiology and Biostatistics, Global Health Sciences, University of California, San Francisco, San Francisco, CA, USA.
Munamato MiriraUnited States Agency for International Development, Mbabane, Swaziland.
Kwashie KudiaborElizabeth Glaser Pediatric AIDS Foundation, MVA Office Park, Corner of Mbhilibhi and Tsekwane Streets, P.O. Box A507, Mbabane, H100, Swaziland.
Michelle M GillElizabeth Glaser Pediatric AIDS Foundation, Washington, DC, USA.
Gugu MaphalalaSwaziland Health Laboratory Services, Ministry of Health, Mbabane, Swaziland.
Godfrey WoelkElizabeth Glaser Pediatric AIDS Foundation, Washington, DC, USA.
Laura GuayElizabeth Glaser Pediatric AIDS Foundation, Washington, DC, USA.

Funding

Int'l Traineeships in AIDS Prevention Studies (ITAPS)R25MH064712 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LINDAN, CHRISTINA P · 2002 to 2018
$3.4M
NIMH NIH HHS R25 MH064712United States Agency for International Development 674-A-00-11-00009-00
6 · The paper itself

Abstract

In Swaziland, no data are available on the rates of HIV infection and HIV-free survival among children at the end of the breastfeeding period. We performed a national crosssectional community survey of children born 18-24 months prior to the study, in randomly selected constituencies in all 4 administrative regions of Swaziland, from April to June 2015. Mother-to-child transmission (MTCT) of HIV and HIV-free survival rates were calculated for all HIV-exposed children. The overall HIV-free survival rate at 18-24 months was 95.9% (95% CI 94.1-97.2). The estimated proportion of HIV infected children among known HIV-exposed children was 3.6% (95% CI 2.4-5.2). Older maternal age, delivering at a health facility, and receiving antenatal antiretroviral drugs were independently associated with reduced risk for child infection or death. The Swaziland program for prevention of MTCT achieved high HIV-free survival (95.9%) and low MTCT (3.6%) rates at 18-24 months of age when Option A (infant prophylaxis) of the WHO 2010 guidelines was implemented.

Indexed as

Disease-Free SurvivalAdultAnti-Retroviral AgentsBreast FeedingCross-Sectional StudiesEswatiniFemaleGuidelines as TopicHIV InfectionsHumansInfantInfant, NewbornInfectious Disease Transmission, VerticalPregnancyPregnancy Complications, InfectiousPrenatal CareAnti-Retroviral AgentsHIV-free survivalMother-to-child transmission (MTCT) of HIVPrevention of mother-to-child transmission (PMTCT) of HIV

Identifiers

PMID29696404
PMCPMC6045958

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.