ReviewEuropean journal of nutrition2018
Put "gender glasses" on the effects of phenolic compounds on cardiovascular function and diseases.
Review in European journal of nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Pooled it
- Pharmacokinetics and bioavailability of hydroxytyrosol are dependent on the food matrix in humans.European journal of nutrition · 2021Trial
- Review
- Changes in food during the COVID-19 pandemic: The different roles of stress and depression in women and men.Nutrition (Burbank, Los Angeles County, Calif.) · 2023Article
- Dietary Antioxidants, Quality of Nutrition and Cardiovascular Characteristics among Omnivores, Flexitarians and Vegetarians in Poland-The Results of Multicenter National Representative Survey WOBASZ.Antioxidants (Basel, Switzerland) · 2023Article
- The Impact of Sex and Gender in Medicine and Pharmacology.Handbook of experimental pharmacology · 2023Article
- Sex Differences in X-ray-Induced Endothelial Damage: Effect of Taurine and N-Acetylcysteine.Antioxidants (Basel, Switzerland) · 2022Article
- Physical Activity and Diet in Older Women: A Narrative Review.Journal of clinical medicine · 2022Review
- Identification and Quantification of Urinary Microbial Phenolic Metabolites by HPLC-ESI-LTQ-Orbitrap-HRMS and Their Relationship with Dietary Polyphenols in Adolescents.Antioxidants (Basel, Switzerland) · 2022Article
- Polyphenols, Olive oil and Colonrectal cancer: the effect of Mediterranean Diet in the prevention.Acta bio-medica : Atenei Parmensis · 2022Article
- The Person's Care Requires a Sex and Gender Approach.Journal of clinical medicine · 2021Review
- Article
- Comment on "Western Dietary Pattern Antioxidant Intakes and Oxidative Stress: Importance during the SARS-CoV-2/COVID-19 Pandemic".Advances in nutrition (Bethesda, Md.) · 2021Article
- Effect of Hydrolysable Tannins and Anthocyanins on Recurrent Urinary Tract Infections in Nephropathic Patients: Preliminary Data.Nutrients · 2021Article
- Berry-Derived Polyphenols in Cardiovascular Pathologies: Mechanisms of Disease and the Role of Diet and Sex.Nutrients · 2021Review
- Espresso coffee, caffeine and colon cancer.World journal of gastrointestinal oncology · 2020Article
- Mediterranean Diet Nutrients to Turn the Tide against Insulin Resistance and Related Diseases.Nutrients · 2020Review
- Review
- Cardioprotective Effects of Dietary Phytochemicals on Oxidative Stress in Heart Failure by a Sex-Gender-Oriented Point of View.Oxidative medicine and cellular longevity · 2020Review
- Platelet Responses in Cardiovascular Disease: Sex-Related Differences in Nutritional and Pharmacological Interventions.Cardiovascular therapeutics · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
introductionThe influence of sex and gender is particularly relevant in cardiovascular diseases (CVD) as well as in several aspects of drug pharmacodynamics and pharmacokinetics. Anatomical and physiological differences between the sexes may influence the activity of many drugs, including the possibility of their interaction with other drugs, bioactive compounds, foods and beverages. Phenolic compounds could interact with our organism at organ, cellular, and molecular levels triggering a preventive action against chronic diseases, including CVD.
resultsThis article will review the role of sex on the activity of these bioactive molecules, considering the existence of sex differences in oxidative stress. It describes the pharmacokinetics of phenolic compounds, their effects on vessels, on cardiovascular system, and during development, including the role of nuclear receptors and microbiota.
conclusionsAlthough there is a large gap between the knowledge of the sex differences in the phenolic compounds' activity and safety, and the urgent need for more research, available data underlie the possibility that plant-derived phenolic compounds could differently influence the health of male and female subjects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.