Evidence map›Paper›PMID 29696377›Full record

ArticleJournal of mathematical biology2018

The effect of sexual transmission on Zika virus dynamics.

C M Saad-Roy, Junling Ma, P van den Driessche

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of mathematical biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Dynamics in a simple evolutionary-epidemiological model for the evolution of an initial asymptomatic infection stage.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

C M Saad-RoyDepartment of Mathematics and Statistics, University of Victoria, Victoria, BC, V8W 2Y2, Canada. saadroy@uvic.ca.ORCID 0000-0002-2217-3071
Junling MaDepartment of Mathematics and Statistics, University of Victoria, Victoria, BC, V8W 2Y2, Canada.
P van den DriesscheDepartment of Mathematics and Statistics, University of Victoria, Victoria, BC, V8W 2Y2, Canada.
University of Victoria · CA

Funding

Natural Sciences and Engineering Research Council of Canada DiscoveryNatural Sciences and Engineering Research Council of Canada USRA
6 · The paper itself

Abstract

Zika virus is a human disease that may lead to neurological disorders in affected individuals, and may be transmitted vectorially (by mosquitoes) or sexually. A mathematical model of Zika virus transmission is formulated, taking into account mosquitoes, sexually active males and females, inactive individuals, and considering both vector transmission and sexual transmission from infectious males to susceptible females. Basic reproduction numbers are computed, and disease control strategies are evaluated. The effect of the incidence function used to model sexual transmission from infectious males to susceptible females is investigated. It is proved that for such functions that are sublinear, if the basic reproduction [Formula: see text], then the disease dies out and [Formula: see text] is a sharp threshold. Moreover, under certain conditions on model parameters and assuming mass action incidence for sexual transmission, it is proved that if [Formula: see text], there exists a unique endemic equilibrium that is globally asymptotically stable. However, under nonlinear incidence, it is shown that for certain functions backward bifurcation and Hopf bifurcation may occur, giving rise to subthreshold equilibria and periodic solutions, respectively. Numerical simulations for various parameter values are displayed to illustrate these behaviours.

Indexed as

Models, BiologicalAnimalsBasic Reproduction NumberComputer SimulationDisease SusceptibilityFemaleHumansIncidenceLinear ModelsMaleMathematical ConceptsMosquito VectorsNonlinear DynamicsSexually Transmitted Diseases, ViralZika VirusZika Virus InfectionBackward bifurcationGlobal stabilityHopf bifurcationZika virus

Identifiers

PMID29696377
OpenAlexW2801827131

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.