Evidence map›Paper›PMID 29696346›Full record

ReviewHerzschrittmachertherapie & Elektrophysiologie2018

Orthostatic intolerance and postural tachycardia syndrome: new insights into pathophysiology and treatment.

Mohammed Ruzieh, Blair P Grubb

Abstract readReview
PubMed Publisher
In one paragraph

Review in Herzschrittmachertherapie & Elektrophysiologie, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Clinical phenotype,Frontiers in immunology · 2024
    Article
  6. Observational
  7. Article
  8. Article
  9. Editorial: Autonomic Neuropathy and Cardiovascular Disease in Aging.The journal of nutrition, health & aging · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Mohammed RuziehCardiology, The Pennsylvania State Heart and Vascular Institute, Hershey, PA, USA.
Blair P GrubbDivision of Cardiovascular Medicine, The University of Toledo Medical Center, 3000 Arlington Ave., 43614, Toledo, OH, USA. Blair.Grubb@utoledo.edu.
Penn State Milton S. Hershey Medical Center · USUniversity of Toledo Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orthostatic intolerance is characterized by symptoms of light-headedness or syncope that is provoked upon standing or in an upright posture. It is most commonly caused by postural orthostatic tachycardia syndrome (POTS) or orthostatic hypotension (OH). Its pathophysiology is complex and commonly involves abnormal autonomic nervous system regulation, autoimmunity, a hyperadrenergic state, and hypovolemia. This article reviews the pathophysiology underlying orthostatic intolerance, as well as the current treatment available.

Indexed as

Hypotension, OrthostaticOrthostatic IntolerancePostural Orthostatic Tachycardia SyndromeHumansPostureTachycardiaAutoimmunityHypovolemiaOrthostatic hypotensionPathophysiologyPostural tachycardia syndrome

Identifiers

PMID29696346
OpenAlexW2801367853

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.