Evidence map›Paper›PMID 29696183›Full record

ArticleContemporary clinical trials communications2017

AExaCTT - Aerobic Exercise and Consecutive Task-specific Training for the upper limb after stroke: Protocol for a randomised controlled pilot study.

Sarah R Valkenborghs, Milanka M Visser, Ashlee Dunn, Kirk I Erickson, Michael Nilsson, Robin Callister, Paulette van Vliet

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary clinical trials communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Physical fitness training for stroke patients.The Cochrane database of systematic reviews · 2020
    Pooled it
  2. Feasibility and efficacy of an early sensory-motor rehabilitation program on hand function in patients with stroke: a pilot, single-subject experimental design.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Sarah R ValkenborghsPriority Research Centre for Physical Activity and Nutrition, University of Newcastle, Callaghan, NSW 2308, Australia.
Milanka M VisserPriority Research Centre for Stroke and Brain Injury, Hunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia.
Ashlee DunnPriority Research Centre for Physical Activity and Nutrition, University of Newcastle, Callaghan, NSW 2308, Australia.
Kirk I EricksonDepartment of Psychology, University of Pittsburgh, Pittsburgh, PA, United States.
Michael NilssonPriority Research Centre for Stroke and Brain Injury, Hunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia.
Robin CallisterPriority Research Centre for Physical Activity and Nutrition, University of Newcastle, Callaghan, NSW 2308, Australia.
Paulette van VlietPriority Research Centre for Stroke and Brain Injury, Hunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia.
Hunter Medical Research Institute · AUUniversity of Newcastle Australia · AUUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Motor function may be enhanced if aerobic exercise is paired with motor training. One potential mechanism is that aerobic exercise increases levels of brain-derived neurotrophic factor (BDNF), which is important in neuroplasticity and involved in motor learning and motor memory consolidation. This study will examine the feasibility of a parallel-group assessor-blinded randomised controlled trial investigating whether task-specific training preceded by aerobic exercise improves upper limb function more than task-specific training alone, and determine the effect size of changes in primary outcome measures. People with upper limb motor dysfunction after stroke will be allocated to either task-specific training or aerobic exercise and consecutive task-specific training. Both groups will perform 60 hours of task-specific training over 10 weeks, comprised of 3 × 1 hour sessions per week with a therapist and 3 × 1 hours of home-based self-practice per week. The combined intervention group will also perform 30 minutes of aerobic exercise (70-85%HR

Indexed as

6MWT, Six Minute Walk TestAerobic exerciseARAT, Action Research Arm TestBDNF, brain-derived neurotrophic factorCERT, Consensus on Exercise Reporting TemplateCM, centimetreCONSORT, Consolidated Standards of Reporting TrialsECG, electrocardiographyELISA, enzyme-linked immunosorbent assayFAS, Fatigue Assessment ScaleGP, general practitionerHRmax, age-predicted maximal heart rate maximumHRpeak, peak heart rateIPAQ, International Physical Activity QuestionnaireMAL, Motor Activity LogmL.kg−1.min−1, millilitres per kilogram per minuteMotor functionMRI, magnetic resonance imagingMS, Microsoftm/s, millimetres per secondNAA, N-acetyl AspartatePD, Peak DecelerationPV, Peak VelocityREDCap, Research Electronic Data Capturereps, repetitionsRPE, rating of perceived exertionRPM, revolutions per minuteSIS, Stroke Impact Scales, secondsStrokeTask-specific trainingVO2, oxygen uptakeVO2peak, peak oxygen uptakeWMFT, Wolf Motor Function Test

Identifiers

PMID29696183
PMCPMC5898578
OpenAlexW2738671936

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.