Evidence map›Paper›PMID 29696095›Full record

ArticleInterface focus2018

Improving the glial differentiation of human Schwann-like adipose-derived stem cells with graphene oxide substrates.

Andrea Francesco Verre, Alessandro Faroni, Maria Iliut, Claudio Silva, Cristopher Muryn, Adam J Reid, Aravind Vijayaraghavan

Abstract read
In one paragraph

Article in Interface focus, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Biomedical Applications of Graphene-Based Structures.Nanomaterials (Basel, Switzerland) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrea Francesco VerreSchool of Materials and National Graphene Institute, University of Manchester, Manchester M13 9PL, UK.
Alessandro FaroniBlond McIndoe Laboratories, Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PL, UK.ORCID 0000-0003-4435-6423
Maria IliutSchool of Materials and National Graphene Institute, University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0003-0786-6408
Claudio SilvaSchool of Materials and National Graphene Institute, University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0003-4331-3755
Cristopher MurynSchool of Chemistry, University of Manchester, Manchester M13 9PL, UK.
Adam J ReidBlond McIndoe Laboratories, Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PL, UK.ORCID 0000-0003-1752-3302
Aravind VijayaraghavanSchool of Materials and National Graphene Institute, University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0001-8289-2337

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is urgent need to improve the clinical outcome of peripheral nerve injury. Many efforts are directed towards the fabrication of bioengineered conduits, which could deliver stem cells to the site of injury to promote and guide peripheral nerve regeneration. The aim of this study is to assess whether graphene and related nanomaterials can be useful in the fabrication of such conduits. A comparison is made between graphene oxide (GO) and reduced GO substrates. Our results show that the graphene substrates are highly biocompatible, and the reduced GO substrates are more effective in increasing the gene expression of the biomolecules involved in the regeneration process compared to the other substrates studied.

Indexed as

adipose stem cellsglial differentiationgraphene

Identifiers

PMID29696095
PMCPMC5915665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.