ArticleFrontiers in immunology2018
Cutaneous Vasculitis and Recurrent Infection Caused by Deficiency in Complement Factor I.
Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Complete Complement Factor I (CFI) deficiency: a systematic review of forty-nine patients including three novel cases.BMC immunology · 2025Pooled it
- Commentary: Anti-endothelial cell antibodies in pathogenesis of vasculitis.Frontiers in immunology · 2026Article
- Rheumatologic and Autoimmune Features of Inborn Errors of Immunity: Implications for Diagnosis and Management.Journal of human immunity · 2025Article
- Integrated comparison of the mRNAome in cartilage, synovium, and macrophages in osteoarthritis.Zeitschrift fur Rheumatologie · 2024Article
- Rare genetic causes of meningitis and encephalitis.Encephalitis (Seoul, Korea) · 2022Review
- Vasculitis in a patient with mevalonate kinase deficiency (MKD): a case report.Pediatric rheumatology online journal · 2021Article
- Case Report: Meningoencephalitis With Thrombotic Occlusive Vasculopathy in a Young EBV-Naïve Boy Is Associated With a NovelFrontiers in immunology · 2021Article
- Vasculitis as a Major Morbidity Factor in Patients With Partial RAG Deficiency.Frontiers in immunology · 2020Article
- Secondary C1q Deficiency in Activated PI3Kδ Syndrome Type 2.Frontiers in immunology · 2019Article
- Classical and Non-classical Presentations of Complement Factor I Deficiency: Two Contrasting Cases Diagnosed via Genetic and Genomic Methods.Frontiers in immunology · 2019Article
- Cutaneous Vasculitis and Digital Ischaemia Caused by Heterozygous Gain-of-Function Mutation inFrontiers in immunology · 2018Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cutaneous leukocytoclastic vasculitis arises from immune complex deposition and dysregulated complement activation in small blood vessels. There are many causes, including dysregulated host response to infection, drug reactions, and various autoimmune conditions. It is increasingly recognised that some monogenic autoinflammatory diseases cause vasculitis, although genetic causes of vasculitis are extremely rare. We describe a child of consanguineous parents who presented with chronic cutaneous leukocytoclastic vasculitis, recurrent upper respiratory tract infection, and hypocomplementaemia. A homozygous p.His380Arg mutation in the complement factor I (CFI) gene
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.