Evidence map›Paper›PMID 29695934›Full record

ArticleCancer management and research2018

MicroRNA-142-3p is involved in regulation of

Yi-Yen Lee, Aliaksandr A Yarmishyn, Mong-Lien Wang, Hsiao-Yun Chen, Shih-Hwa Chiou, Yi-Ping Yang, Chun-Fu Lin, Pin-I Huang, Yi-Wei Chen, Hsin-I Ma and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancer management and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Role of non-coding RNAs in OOncology letters · 2026
    Review
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  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. FAM98A promotes cancer progression in endometrial carcinoma.Molecular and cellular biochemistry · 2019
    Article
  14. Alkylating anticancer agents and their relations to microRNAs.Cancer drug resistance (Alhambra, Calif.) · 2019
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Yi-Yen Lee *Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital.
Aliaksandr A Yarmishyn *Institute of Pharmacology, National Yang-Ming University.
Mong-Lien WangInstitute of Pharmacology, National Yang-Ming University.
Hsiao-Yun ChenDepartment of Medical Research, Taipei Veterans General Hospital.
Shih-Hwa ChiouInstitute of Pharmacology, National Yang-Ming University.
Yi-Ping YangDepartment of Medical Research, Taipei Veterans General Hospital.
Chun-Fu LinDepartment of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital.
Pin-I HuangFaculty of Medicine, National Yang-Ming University.
Yi-Wei ChenFaculty of Medicine, National Yang-Ming University.
Hsin-I MaDepartment of Neurological Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Ming-Teh ChenDepartment of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital.
National Yang Ming Chiao Tung University · TWTri-Service General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlioblastoma multiforme (GBM) is the most malignant brain tumor, and there is no effective treatment strategy. Patients with GBM have a median overall survival of only 14.6 months. Current treatment consists of safe and maximal surgical excision, followed by concurrent chemoradiotherapy and maintenance chemotherapy. There are several obstacles that hinder the effectiveness of this aggressive treatment. Temozolomide (TMZ) is an oral alkylating drug that acts through alkylating the

resultsIn this study, we sought to investigate whether miR-142-3p can regulate

conclusionAbove all, our findings demonstrate that miR-142-3p plays a critical role in regulating

Indexed as

carmustineglioblastomamiR-142-3pO6-methylguanine-DNA methyltransferasetemozolomide

Identifiers

PMID29695934
PMCPMC5903834
OpenAlexW2798237282

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.