Evidence map›Paper›PMID 29695931›Full record

ArticleCancer management and research2018

The role of the pathology department in the preanalytical phase of molecular analyses.

Sergiu Susman, Ioana Berindan-Neagoe, Bobe Petrushev, Radu Pirlog, Ioan-Stefan Florian, Carmen-Mihaela Mihu, Cristian Berce, Lucian Craciun, Ravnit Grewal, Ciprian Tomuleasa

Abstract read
In one paragraph

Article in Cancer management and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Breast cancer in northern Peru: molecular subtypes and HER2 low.Revista peruana de medicina experimental y salud publica · 2024
    Article
  3. The neurobiology of SARS-CoV-2 infection.Nature reviews. Neuroscience · 2024
    Review
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  6. Review
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  8. Review
  9. Article
  10. Evaluation of Formalin Fixation for Tissue Biopsies Using Shear Wave Laser Speckle Imaging System.IEEE journal of translational engineering in health and medicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sergiu SusmanDepartment of Pathology, Imogen Research Center.
Ioana Berindan-NeagoeResearch Center for Functional Genomics and Translational Medicine.
Bobe PetrushevResearch Center for Functional Genomics and Translational Medicine.
Radu PirlogDepartment of Morphological Sciences.
Ioan-Stefan FlorianDepartment of Neurosurgery, Iuliu Hatieganu University of Medicine and Pharmacy.
Carmen-Mihaela MihuDepartment of Morphological Sciences.
Cristian BerceResearch Center for Functional Genomics and Translational Medicine.
Lucian CraciunDepartment of Morphological Sciences.
Ravnit GrewalDepartment of Hematology, Ion Chiricuta Oncology Institute.
Ciprian TomuleasaResearch Center for Functional Genomics and Translational Medicine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After introducing the new molecules for the treatment of patients with tumoral pathology, the therapeutical decision will be taken depending on the molecular profile performed upon the harvested tissues. This major modification makes the molecular and morphological analysis an essential part in the clinical management of patients and the pathologist plays an important role in this process. The quality and reproducibility of the results are imperative today and they depend on both the reliability of the molecular techniques and the quality of the tissue we use in the process. Also, the genomics and proteomics techniques, used increasingly often, require high-quality tissues, and pathology laboratories play a very significant role in the management of all phases of this process. In this paper the parameters which must be followed in order to obtain optimal results within the techniques which analyze nucleic acids and proteins were reviewed.

Indexed as

fixationfreezingmolecular techniquesnucleic acidsproteins

Identifiers

PMID29695931
PMCPMC5903845

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.