ArticleNeuropsychiatric disease and treatment2018
The functional and structural characteristics of the emotion network in alexithymia.
Article in Neuropsychiatric disease and treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Prevalence of alexithymia in Chinese adolescents: a systematic review and meta‑analysis.BMC psychiatry · 2026Pooled it
- How alexithymia shapes functional networks: Insights from a general population study.European psychiatry : the journal of the Association of European Psychiatrists · 2026Article
- Alexithymia characteristics are associated with salience network activity in healthy participants: an arterial spin labeling study.Journal of physiological anthropology · 2023Article
- The relationship between alexithymia, interoception, and neural functional connectivity during facial expression processing in autism spectrum disorder.Neuropsychologia · 2023Article
- Aggression, Alexithymia and Sense of Coherence in a Sample of Schizophrenic Outpatients.Healthcare (Basel, Switzerland) · 2022Article
- Convergent and Divergent Structural Connectivity of Brain White Matter Network Between Patients With Erectile Dysfunction and Premature Ejaculation: A Graph Theory Analysis Study.Frontiers in neurology · 2022Article
- Decreased Functional Connectivity in Insular Subregions in Depressive Episodes of Bipolar Disorder and Major Depressive Disorder.Frontiers in neuroscience · 2018Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlexithymia is a multifaceted personality trait characterized by emotional dysfunction.
methodsIn this study, the functional and structural features of the emotion network in alexithymia were investigated using resting-state functional MRI (rsfMRI), voxel-based morphometry (VBM), functional connectivity (FC) analysis, and diffusion tensor imaging (DTI). Alexithymic and non-alexithymic students were recruited from the local university. The intrinsic neural activity and gray matter density of the brain regions in the emotion network were measured using rsfMRI and VBM; the FC and structural connectivity of the brain regions in the emotion network were measured using FC analysis and DTI.
resultsThe altered intrinsic neural activity in V1, rostral dorsal anterior cingulate cortex, and left amygdala, and the weak FC between V1 and left superior temporal gyrus and V1 and left paracentral lobule in alexithymia subjects were identified. However, no alteration of the structure and structural connectivity of the emotion network was identified.
conclusionThe results indicated that the development of alexithymia might have been caused only by slight alteration of the neural activity. Furthermore, the results suggest that noninvasive treatment technologies for improving the brain activity are suitable for alexithymic individuals.
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