Evidence map›Paper›PMID 29695904›Full record

ReviewInternational journal of nanomedicine2018

Antimicrobial hydrogels: promising materials for medical application.

Kerong Yang, Qing Han, Bingpeng Chen, Yuhao Zheng, Kesong Zhang, Qiang Li, Jincheng Wang

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed
21.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed, 386 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Mechanism, Efficacy, and Safety of Natural Antibiotics.Antibiotics (Basel, Switzerland) · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Smart Materials Design for Antibacterial Application.Pharmaceutical nanotechnology · 2025
    Review
  15. Review
  16. Antimicrobial ZnGels (Basel, Switzerland) · 2024
    Article
  17. Article
  18. Article
  19. An Overview of Wound Dressing Materials.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  20. Review

54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kerong YangDepartment of Orthopedics, The Second Hospital, Jilin University, Changchun, Jilin, People's Republic of China.
Qing HanDepartment of Orthopedics, The Second Hospital, Jilin University, Changchun, Jilin, People's Republic of China.
Bingpeng ChenDepartment of Orthopedics, The Second Hospital, Jilin University, Changchun, Jilin, People's Republic of China.
Yuhao ZhengDepartment of Orthopedics, The Second Hospital, Jilin University, Changchun, Jilin, People's Republic of China.
Kesong ZhangDepartment of Orthopedics, The Second Hospital, Jilin University, Changchun, Jilin, People's Republic of China.
Qiang LiDepartment of Orthopedics, The Second Hospital, Jilin University, Changchun, Jilin, People's Republic of China.
Jincheng WangDepartment of Orthopedics, The Second Hospital, Jilin University, Changchun, Jilin, People's Republic of China.
Second Affiliated Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid emergence of antibiotic resistance in pathogenic microbes is becoming an imminent global public health problem. Local application of antibiotics might be a solution. In local application, materials need to act as the drug delivery system. The drug delivery system should be biodegradable and prolonged antibacterial effect should be provided to satisfy clinical demand. Hydrogel is a promising material for local antibacterial application. Hydrogel refers to a kind of biomaterial synthesized by a water-soluble natural polymer or a synthesized polymer, which turns into gel according to the change in different signals such as temperature, ionic strength, pH, ultraviolet exposure etc. Because of its high hydrophilicity, unique three-dimensional network, fine biocompatibility and cell adhesion, hydrogel is one of the suitable biomaterials for drug delivery in antimicrobial areas. In this review, studies from the past 5 years were reviewed, and several types of antimicrobial hydrogels according to different ingredients, different preparations, different antimicrobial mechanisms, different antimicrobial agents they contained and different applications, were summarized. The hydrogels loaded with metal nanoparticles as a potential method to solve antibiotic resistance were highlighted. Finally, future prospects of development and application of antimicrobial hydrogels are suggested.

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsDrug Delivery SystemsHumansHydrogelsMetal NanoparticlesPolymersTemperatureAnti-Bacterial AgentsAnti-Infective AgentsHydrogelsPolymersantibioticsdrug deliveryhydrogelsinfectionnanomaterialsnanoparticles

Identifiers

PMID29695904
PMCPMC5905846
OpenAlexW2798113757

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.