ArticleScientific reports2018
Associations of obstructive sleep apnea with truncal skeletal muscle mass and density.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 32 citations in OpenAlex.
- Sleep-disordered breathing as a risk factor for sarcopenia in the elderly: a narrative review.Sleep & breathing = Schlaf & Atmung · 2026Review
- Obstructive sleep apnea is associated with altered skeletal muscle composition using computed tomography-derived indices.Sleep & breathing = Schlaf & Atmung · 2026Article
- Time to Reset: The Interplay Between Circadian Rhythms and Redox Homeostasis in Skeletal Muscle Ageing and Systemic Health.Antioxidants (Basel, Switzerland) · 2025Review
- Sleep Architecture, Muscle Function, and Daily Life Activities in Patients with Sarcopenia.Sleep science (Sao Paulo, Brazil) · 2025Article
- Body Composition Analysis in Obstructive Sleep Apnea: A Cross-Sectional Study Using Bioelectrical Impedance Analysis.The clinical respiratory journal · 2025Article
- Muscle and Fat Composition in OSA: A CT-Based Study.Journal of clinical medicine · 2025Article
- Causal associations between Sarcopenia-related traits and obstructive sleep apnea: a mendelian randomization study.Aging clinical and experimental research · 2025Article
- Review
- Associations of fat, bone, and muscle indices with disease severity in patients with obstructive sleep apnea hypopnea syndrome.Sleep & breathing = Schlaf & Atmung · 2025Article
- Associations between body composition, hydration status, and sleep architecture in obstructive sleep apnea.Frontiers in endocrinology · 2025Article
- Causal Associations Between Sleep Traits and Low Grip Strength: A Bidirectional Mendelian Randomization Study.Nature and science of sleep · 2024Article
- Sex Differences in Obstructive Sleep Apnea by Bioelectrical Impedance Analysis.Journal of clinical neurology (Seoul, Korea) · 2021Article
- Association of sleep disturbances with sarcopenia and its defining components: the ELSA-Brasil study.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2021Article
- Metabolic Syndrome and Abnormal Peri-Organ or Intra-Organ Fat (APIFat) Deposition in Chronic Obstructive Pulmonary Disease: An Overview.Metabolites · 2020Review
- Re-Setting the Circadian Clock Using Exercise against Sarcopenia.International journal of molecular sciences · 2020Review
- Associations of OSA and Nocturnal Hypoxemia with Strength and Body Composition in Community Dwelling Middle Aged and Older Men.Nature and science of sleep · 2020Article
- Circadian rhythm disruption is associated with an increased risk of sarcopenia: a nationwide population-based study in Korea.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sarcopenia has been associated with several conditions relevant to obstructive sleep apnea (OSA), such as aging and obesity, but a direct relationship between OSA and skeletal muscle alterations has not been identified. This study investigated associations between computed tomography (CT)-measured skeletal muscle indices and OSA severity. Analyzed were 334 patients who underwent polysomnography to diagnose OSA. Lumbar skeletal muscles were assessed with CT for the skeletal muscle mass index (SMI, cross-sectional area, normalized for height squared) and skeletal muscle density (SMD, fat infiltration). The apnea-hypopnea index (AHI) correlated positively with the SMI and negatively with SMD in both men and women. The AHI was weakly associated with SMI only in men (β = 0.11, P = 0.017) after adjustment for the body mass index (BMI) (BMI: β = 0.61, P < 0.001 in men, β = 0.65, P < 0.001 in women). The association of AHI and SMD was not significant after adjustment for BMI (BMI: β = -0.42, P < 0.001 in men, β = -0.64, P < 0.001 in women). Severity of OSA correlated with increases in skeletal muscle mass rather than muscle depletion and skeletal muscle adiposity. These associations were limited compared with the stronger associations between obesity and skeletal muscles.
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Registered trials
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