Evidence map›Paper›PMID 29695704›Full record

ArticleNutrition & diabetes2018

Human adipose tissue protein analyses using capillary western blot technology.

Jin Lu, Carolyn C Allred, Michael D Jensen

Open access · goldAbstract read
In one paragraph

Article in Nutrition & diabetes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Insulin-Stimulated Muscle Glucose Uptake and Insulin Signaling in Lean and Obese Humans.The Journal of clinical endocrinology and metabolism · 2021
    Article
  17. Article
  18. Article
  19. Hesperidin increases theJournal of advanced pharmaceutical technology & research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Jin LuDepartment of Endocrinology, Changhai Hospital, Second Military Medical University, Shanghai, P.R. China.
Carolyn C AllredDivision of Endocrinology, Diabetes & Metabolism, Endocrine Research Unit, Mayo Clinic College of Medicine, Rochester, MN, USA.
Michael D JensenDivision of Endocrinology, Diabetes & Metabolism, Endocrine Research Unit, Mayo Clinic College of Medicine, Rochester, MN, USA. jensen@mayo.edu.
Mayo Clinic · USSecond Military Medical University · CN

Funding

MAYO CLINIC CENTER FOR TRANSLATIONAL SCIENCE ACTIVITIESUL1RR024150 · NCRR · MAYO CLINIC ROCHESTER · PI RIZZA, ROBERT A. · 2006 to 2011
$66.4M
REGIONAL FATTY ACID METABOLISM IN HUMANSR01DK045343 · NIDDK · MAYO CLINIC ROCHESTER · PI MICHAEL D. JENSEN · 1992 to 2026
$12.9M
FFA METABOLISM IN DIFFERENT TYPES OF HUMAN OBESITYR01DK040484 · NIDDK · MAYO CLINIC ROCHESTER · PI MICHAEL D. JENSEN · 1993 to 2026
$8.2M
Free Fatty Acid Metabolism in Different Types of Human ObesityR37DK040484 · NIDDK · MAYO CLINIC ROCHESTER · PI JENSEN, MICHAEL D. · 2003 to 2012
$4.1M
NCRR NIH HHS UL1 RR024150NIDDK NIH HHS R01 DK040484NIDDK NIH HHS R01 DK045343NIDDK NIH HHS R37 DK040484
6 · The paper itself

Abstract

A capillary western blot (Wes®) technology has recently been validated for analyses of cell culture lysate proteins, but whether it is reliable for human tissue proteins is unknown. We compared traditional western blotting to the Wes® capillary western method to quantitate the relative amount of human adipose tissue CD36, the ratio of phosphorylated Erk1/2 (pErk1/2) to total Erk1/2 during insulin clamp or after niacin treatment and the fold increase in pAkt

Indexed as

Adipose TissueBlotting, WesternHumansMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3PhosphorylationProto-Oncogene Proteins c-aktReproducibility of ResultsMAPK1 protein, humanMAPK3 protein, humanMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Proto-Oncogene Proteins c-akt

Identifiers

PMID29695704
PMCPMC5916899
OpenAlexW2773923980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.