Evidence map›Paper›PMID 29695686›Full record

ReviewMolekuliarnaia biologiia

[Functional Characterization of Septin Complexes].

K A Akhmetova, I N Chesnokov, S A Fedorova

Abstract readReview
In one paragraph

Review in Molekuliarnaia biologiia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Reduced Expression of Septin7 Hinders Skeletal Muscle Regeneration.International journal of molecular sciences · 2023
    Article
  6. Article
  7. Article
  8. Septins in Infections: Focus on Viruses.Pathogens (Basel, Switzerland) · 2021
    Review
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

K A AkhmetovaInstitute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090 Russia.
I N ChesnokovUniversity of Alabama at Birmingham, Birmingham, 35294 USA.
S A FedorovaInstitute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090 Russia.

Funding

The role of Orc6 in DNA replication and cytokinesis.R01GM121449 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CHESNOKOV, IGOR N · 2017 to 2023
$2.6M
NIGMS NIH HHS R01 GM121449
6 · The paper itself

Abstract

Septins belong to a family of conserved GTP-binding proteins found in majority of eukaryotic species except for higher plants. Septins form nonpolar complexes that further polymerize into filaments and associate with cell membranes, thus comprising newly acknowledged cytoskeletal system. Septins participate in a variety of cell processes and contribute to various pathophysiological states, including tumorigenesis and neurodegeneration. Here, we review the structural and functional properties of septins and the regulation of their dynamics with special emphasis on the role of septin filaments as a cytoskeletal system and its interaction with actin and microtubule cytoskeletons. We also discuss how septins compartmentalize the cell by forming local protein-anchoring scaffolds and by providing barriers for the lateral diffusion of the membrane proteins.

Indexed as

AnimalsCell MembraneHumansMultienzyme ComplexesNeoplasm ProteinsNeoplasmsNeurodegenerative DiseasesSeptinsMultienzyme ComplexesNeoplasm ProteinsSeptinsseptin complexesseptin filamentsseptinsseptin scaffold

Identifiers

PMID29695686
PMCPMC6027748

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.