Evidence map›Paper›PMID 29695586›Full record

ArticleEndocrine-related cancer2018

GREB1 isoforms regulate proliferation independent of ERα co-regulator activities in breast cancer.

Corinne N Haines, Kara M Braunreiter, Xiaokui Molly Mo, Craig J Burd

Open access · bronzeAbstract read
In one paragraph

Article in Endocrine-related cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Corinne N HainesDepartment of Molecular GeneticsThe Ohio State University, Columbus, Ohio, USA.
Kara M BraunreiterDepartment of Molecular GeneticsThe Ohio State University, Columbus, Ohio, USA.
Xiaokui Molly MoCenter for BiostatisticsThe Ohio State University, Wexner Medical Center, Columbus, Ohio, USA.
Craig J BurdDepartment of Molecular GeneticsThe Ohio State University, Columbus, Ohio, USA Craig.Burd@osumc.edu.
The Ohio State University · USThe Ohio State University Wexner Medical Center · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
NCI NIH HHS P30 CA016058
6 · The paper itself

Abstract

Activation of the transcription factor estrogen receptor α (ERα) and the subsequent regulation of estrogen-responsive genes play a crucial role in the development and progression of the majority of breast cancers. One gene target of ERα, growth regulation by estrogen in breast cancer 1 (

Indexed as

Breast NeoplasmsCell Line, TumorCell ProliferationEstrogen Receptor alphaFemaleHumansNeoplasm ProteinsProtein IsoformsEstrogen Receptor alphaGREB1 protein, humanNeoplasm ProteinsProtein Isoformsbreast cancerestrogen receptorgene expressionproliferation

Identifiers

PMID29695586
PMCPMC7158201
OpenAlexW2800015932

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.