Evidence map›Paper›PMID 29695583›Full record

ArticlePediatrics2018

Relevance of Abusive Head Trauma to Intracranial Hemorrhages and Bleeding Disorders.

James D Anderst, Shannon L Carpenter, Rodney Presley, Molly Curtin Berkoff, Allison P Wheeler, Robert F Sidonio, J Michael Soucie

Open access · greenAbstract read
In one paragraph

Article in Pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Neurological Complications Associated with Hereditary Bleeding Disorders.Current neurology and neuroscience reports · 2023
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

James D AnderstDepartment of Pediatrics, Children's Mercy Hospital, Kansas City, Missouri; jdanderst@cmh.edu.
Shannon L CarpenterDepartment of Pediatrics, Children's Mercy Hospital, Kansas City, Missouri.
Rodney PresleyDivisions of Sexually Transmitted Disease Prevention and.
Molly Curtin BerkoffDepartment of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Allison P WheelerDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee; and.
Robert F SidonioDepartment of Pediatrics, Children's Healthcare of Atlanta, Emory University, Atlanta, Georgia.
J Michael SoucieBlood Disorders, Centers for Disease Control and Prevention, Atlanta, Georgia.
Children's Mercy Hospital · USCenters for Disease Control and Prevention · USChildren's Healthcare of Atlanta · USUniversity of North Carolina at Chapel Hill · USVanderbilt University Medical Center · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundBleeding disorders and abusive head trauma (AHT) are associated with intracranial hemorrhage (ICH), including subdural hemorrhage (SDH). Because both conditions often present in young children, the need to screen for bleeding disorders would be better informed by data that include trauma history and are specific to young children. The Universal Data Collection database contains information on ICH in subjects with bleeding disorders, including age and trauma history. Study objectives were to (1) characterize the prevalence and calculate the probabilities of any ICH, traumatic ICH, and nontraumatic ICH in children with congenital bleeding disorders; (2) characterize the prevalence of spontaneous SDH on the basis of bleeding disorder; and (3) identify cases of von Willebrand disease (vWD) that mimic AHT.

methodsWe reviewed subjects <4 years of age in the Universal Data Collection database. ICH was categorized on the basis of association with trauma. Prevalence and probability of types of ICH were calculated for each bleeding disorder.

resultsOf 3717 subjects, 255 (6.9%) had any ICH and 206 (5.5%) had nontraumatic ICH. The highest prevalence of ICH was in severe hemophilia A (9.1%) and B (10.7%). Of the 1233 subjects <2 years of age in which the specific location of any ICH was known, 13 (1.1%) had spontaneous SDH (12 with severe hemophilia; 1 with type 1 vWD). The findings in the subject with vWD were not congruent with AHT.

conclusionsIn congenital bleeding disorders, nontraumatic ICH occurs most commonly in severe hemophilia. In this study, vWD is not supported as a "mimic" of AHT.

Indexed as

Blood Coagulation Disorders, InheritedChild AbuseChild, PreschoolCraniocerebral TraumaDatabases, FactualDiagnosis, DifferentialFemaleHematoma, SubduralHumansInfantIntracranial HemorrhagesMalePrevalenceRetrospective StudiesUnited States

Identifiers

PMID29695583
PMCPMC5985662
OpenAlexW2801249590

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.