Evidence map›Paper›PMID 29695572›Full record

ArticleIn vivo (Athens, Greece)

The Feasibility and Efficacy of Laparoscopic Extended Total Mesorectal Excision for Locally Advanced Lower Rectal Cancer.

Takashi Nonaka, Akiko Fukuda, Kyoichiro Maekawa, Shigeki Nagayoshi, Takayuki Tokunaga, Mitsutoshi Takatsuki, Tomoo Kitajima, Ken Taniguchi, Hikaru Fujioka

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Takashi NonakaDepartment of Surgery, National Hospital Organization Nagasaki Medical Center, Nagasaki, Japan tnonaka@nagasaki-u.ac.jp.
Akiko FukudaDepartment of Surgery, National Hospital Organization Nagasaki Medical Center, Nagasaki, Japan.
Kyoichiro MaekawaDepartment of Surgery, National Hospital Organization Nagasaki Medical Center, Nagasaki, Japan.
Shigeki NagayoshiDepartment of Surgery, National Hospital Organization Nagasaki Medical Center, Nagasaki, Japan.
Takayuki TokunagaDepartment of Surgery, National Hospital Organization Nagasaki Medical Center, Nagasaki, Japan.
Mitsutoshi TakatsukiDepartment of Surgery, National Hospital Organization Nagasaki Medical Center, Nagasaki, Japan.
Tomoo KitajimaDepartment of Surgery, National Hospital Organization Nagasaki Medical Center, Nagasaki, Japan.
Ken TaniguchiDepartment of Surgery, National Hospital Organization Nagasaki Medical Center, Nagasaki, Japan.
Hikaru FujiokaDepartment of Surgery, National Hospital Organization Nagasaki Medical Center, Nagasaki, Japan.
Nagasaki Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimExtended total mesorectal excision (ETME) is defined as en bloc resection of the adjacent organs outside the mesorectal fascia, that is indicated in cases with locally advanced lower rectal cancer (T4 tumor). The aim of this study was to evaluate the clinical and oncological outcomes of laparoscopic ETME (L-ETME) for locally advanced lower rectal cancer. PATIENTS AND

methodsThe present study analyzed clinical outcomes and oncological outcomes of 11 consecutive patients who underwent L-ETME for cT4 lower rectal cancer in Nagasaki Medical Center between 2012 and 2015.

resultsOf the 11 patients, 7 underwent neoadjuvant therapy, and 7 underwent pelvic node dissection. One case (7.1%) underwent resection of anterior organs (prostate), 6 cases (54.5%) had resection of the lateral organs (neurovascular bundle, hypogastric nerve, pelvic plexus, ovary, and internal iliac blood vessels) and 4 cases (36.4%) had resection of both anterior and lateral organs. In all cases enrolled in this study, R0 resection was achieved. The median operation time and intraoperative blood loss were 416 min and 350 ml, respectively. The postoperative complication rate was 18.2% (2/11). The 3-year overall survival rate was 79.5%, and the 3-year local recurrence-free survival rate was 87.5%. There was no mortality and no re-operation in this series.

conclusionThe results of the present study suggest that L-ETME is feasible and has efficacy for locally advanced lower rectal cancer.

Indexed as

ColectomyLaparoscopyAgedAged, 80 and overCombined Modality TherapyFemaleHumansLymph Node ExcisionMaleMiddle AgedNeoadjuvant TherapyNeoplasm StagingRectal NeoplasmsReproducibility of ResultsTreatment Outcomeextended TMElaparoscopic surgeryLocally advanced lower rectal cancer

Identifiers

PMID29695572
PMCPMC6000797
OpenAlexW2980455849

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.