Evidence map›Paper›PMID 29695570›Full record

ArticleIn vivo (Athens, Greece)

Predicting Survival After Whole-brain Irradiation for Cerebral Metastases in Patients with Cancer of the Bladder.

Dirk Rades, Liesa Dziggel, Lisa Manig, Stefan Janssen, Mai Trong Khoa, Vuong Ngoc Duong, Vu Huu Khiem, Steven E Schild

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Dirk RadesDepartment of Radiation Oncology, University of Lübeck, Lübeck, Germany rades.dirk@gmx.net.
Liesa DziggelDepartment of Radiation Oncology, University of Lübeck, Lübeck, Germany.
Lisa ManigDepartment of Radiation Oncology, University of Lübeck, Lübeck, Germany.
Stefan JanssenDepartment of Radiation Oncology, University of Lübeck, Lübeck, Germany.
Mai Trong KhoaFaculty of Medicine, Hanoi Medical University, Hanoi, Vietnam.
Vuong Ngoc DuongNuclear Medicine and Oncology Center, Bach Mai Hospital, Hanoi, Vietnam.
Vu Huu KhiemNuclear Medicine and Oncology Center, Bach Mai Hospital, Hanoi, Vietnam.
Steven E SchildDepartment of Radiation Oncology, Mayo Clinic, Scottsdale, AZ, U.S.A.
Bạch Mai Hospital · VNUniversity of Lübeck · DEHanoi Medical University · VNMayo Clinic in Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimThis study aimed to create a predictive tool for estimating the remaining lifespan of patients after whole-brain irradiation (WBI) for cerebral metastases from bladder cancer. PATIENTS AND

methodsIn 34 of these patients clinical parameters were analyzed for survival including age at start of WBI, gender, Karnofsky score, number of cerebral metastases and involvement of extra-cranial sites of metastasis.

resultsInvolvement of extra-cranial sites (14%) and Karnofsky score (9%) showed the greatest difference regarding 6-month survival and were considered for the tool. Points were assigned based on the following: no involvement of extra-cranial sites=1 point, involvement of extra-cranial sites=0 points, Karnofsky score ≥70=1 point, Karnofsky score ≤60=0 points. Patients' scores were 0, 1 or 2 points with 6-month survival rates of 13%, 27% and 50%, respectively.

conclusionBased on two clinical parameters, a tool was developed that may help estimate the lifespan of patients irradiated for cerebral metastases from bladder cancer.

Indexed as

AgedAged, 80 and overBrain NeoplasmsCranial IrradiationFemaleHumansMaleMiddle AgedPrognosisRadiation DosageTreatment OutcomeUrinary Bladder NeoplasmsCancer of the bladdercerebral metastasesestimation of survivalprognostic toolwhole-brain irradiation

Identifiers

PMID29695570
PMCPMC6000788
OpenAlexW2897509377

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.