SynthesisBritish journal of sports medicine2019
How does light-intensity physical activity associate with adult cardiometabolic health and mortality? Systematic review with meta-analysis of experimental and observational studies.
Synthesis in British journal of sports medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06592209 (Body Electric), which is not on this map. Cited by 206 papers, 17 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Body Electric: a Pragmatic Trial Evaluating Movement Breaks As a Public Health Strategy to Mitigate the Harms of Prolonged Sedentary Behavior
Who cites it
206 citing papers in PubMed, 17 syntheses or guidelines pooled it, 480 citations in OpenAlex.
- Physical activity and exercise in primary open-angle glaucoma: a scoping review.Frontiers in physiology · 2026Pooled it
- Evaluating the methods used to examine sitting breaks and their influence on mental load, physical strain, and cognitive performance - a scoping review.Frontiers in physiology · 2026Pooled it
- How Active Are Women in the First Year of Motherhood? A Systematic Review of Device-Measured Physical Activity.Scandinavian journal of medicine & science in sports · 2025Pooled it
- Associations Between Exercise Training, Physical Activity, Sedentary Behaviour and Mortality: An Umbrella Review of Meta-Analyses.Journal of cachexia, sarcopenia and muscle · 2025Pooled it
- Effectiveness of Digital Health Interventions in Promoting Physical Activity Among College Students: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2024Pooled it
- Validity and reliability of self-reported methods for assessment of 24-h movement behaviours: a systematic review.The international journal of behavioral nutrition and physical activity · 2024Pooled it
- Personality and change in physical activity across 3-10 years.Psychology & health · 2024Pooled it
- Pooled it
- Light-intensity physical activity and mental ill health: a systematic review of observational studies in the general population.The international journal of behavioral nutrition and physical activity · 2021Pooled it
- Mechanisms of Impact of Blue Spaces on Human Health: A Systematic Literature Review and Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- Joint associations of accelero-meter measured physical activity and sedentary time with all-cause mortality: a harmonised meta-analysis in more than 44 000 middle-aged and older individuals.British journal of sports medicine · 2020Pooled it
- Exercise/physical activity and health outcomes: an overview of Cochrane systematic reviews.BMC public health · 2020Pooled it
- Predictors of the Acute Postprandial Response to Breaking Up Prolonged Sitting.Medicine and science in sports and exercise · 2020Pooled it
- Exercise as Medicine for Mental and Substance Use Disorders: A Meta-review of the Benefits for Neuropsychiatric and Cognitive Outcomes.Sports medicine (Auckland, N.Z.) · 2020Pooled it
- The Effectiveness of Sedentary Behaviour Reduction Workplace Interventions on Cardiometabolic Risk Markers: A Systematic Review.Sports medicine (Auckland, N.Z.) · 2019Pooled it
- 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.Journal of the American College of Cardiology · 2019Guideline
- Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: systematic review and harmonised meta-analysis.BMJ (Clinical research ed.) · 2019Pooled it
- The role of the 'obligation to help others' within the superwoman schema: implications for physical activity in African American women with low activity levels.Journal of behavioral medicine · 2026Trial
- Metabolomic profiling of intensity-dependent responses to acute exercise in healthy humans.Journal of translational medicine · 2026Trial
- Effect of a behavioral counseling for adoption and maintenance of a physically active lifestyle on long-term mortality in people with type 2 diabetes: post hoc analysis of the Italian Diabetes and Exercise Study_2.Nature communications · 2026Trial
146 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo assess the relationship between time spent in light physical activity and cardiometabolic health and mortality in adults.
designSystematic review and meta-analysis. DATA SOURCES: Searches in Medline, Embase, PsycInfo, CINAHL and three rounds of hand searches. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: Experimental (including acute mechanistic studies and physical activity intervention programme) and observational studies (excluding case and case-control studies) conducted in adults (aged ≥18 years) published in English before February 2018 and reporting on the relationship between light physical activity (<3 metabolic equivalents) and cardiometabolic health outcomes or all-cause mortality. STUDY APPRAISAL AND SYNTHESIS: Study quality appraisal with QUALSYST tool and random effects inverse variance meta-analysis.
resultsSeventy-two studies were eligible including 27 experimental studies (and 45 observational studies). Mechanistic experimental studies showed that short but frequent bouts of light-intensity activity throughout the day reduced postprandial glucose (-17.5%; 95% CI -26.2 to -8.7) and insulin (-25.1%; 95% CI -31.8 to -18.3) levels compared with continuous sitting, but there was very limited evidence for it affecting other cardiometabolic markers. Three light physical activity programme intervention studies (n ranging from 12 to 58) reduced adiposity, improved blood pressure and lipidaemia; the programmes consisted of activity of >150 min/week for at least 12 weeks. Six out of eight prospective observational studies that were entered in the meta-analysis reported that more time spent in daily light activity reduced risk of all-cause mortality (pooled HR 0.71; 95% CI 0.62 to 0.83).
conclusionsLight-intensity physical activity could play a role in improving adult cardiometabolic health and reducing mortality risk. Frequent short bouts of light activity improve glycaemic control. Nevertheless, the modest volume of the prospective epidemiological evidence base and the moderate consistency between observational and laboratory evidence inhibits definitive conclusions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.