Evidence map›Paper›PMID 29695412›Full record

ArticleThe Journal of general physiology2018

Dimerization of the voltage-sensing phosphatase controls its voltage-sensing and catalytic activity.

Vamseedhar Rayaprolu, Perrine Royal, Karen Stengel, Guillaume Sandoz, Susy C Kohout

Abstract read
In one paragraph

Article in The Journal of general physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The S1 helix is a VIP in VSP.The Journal of general physiology · 2024
    Article
  6. Voltage sensors of a NaNature communications · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Engineering an enhanced voltage-sensing phosphatase.The Journal of general physiology · 2020
    Article
  12. Article
  13. Article
  14. Article
  15. Molecular mechanisms of coupling to voltage sensors in voltage-evoked cellular signals.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2019
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vamseedhar RayaproluDepartment of Cell Biology and Neuroscience, Montana State University, Bozeman, MT.ORCID 0000-0002-2823-2984
Perrine RoyalCentre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Medicale, iBV, Université Côte d'Azur, Valbonne, France.
Karen StengelDepartment of Cell Biology and Neuroscience, Montana State University, Bozeman, MT.ORCID 0000-0002-8764-9122
Guillaume SandozCentre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Medicale, iBV, Université Côte d'Azur, Valbonne, France.ORCID 0000-0003-1251-0852
Susy C KohoutDepartment of Cell Biology and Neuroscience, Montana State University, Bozeman, MT skohout@montana.edu.ORCID 0000-0002-8159-8934

Funding

Research Core (Developmental Research Project Program)P20GM103474 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Jeffrey Good · 2012 to 2026
$60.0M
Molecular mechanisms behind the voltage sensing phosphatase signalingR01GM111685 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI KOHOUT, SUSY C · 2015 to 2018
$1.1M
NIGMS NIH HHS P20 GM103474NIGMS NIH HHS R01 GM111685
6 · The paper itself

Abstract

Multimerization is a key characteristic of most voltage-sensing proteins. The main exception was thought to be the

Indexed as

Protein MultimerizationAnimalsCatalytic DomainHEK293 CellsHumansMembrane PotentialsPhosphatidylinositol PhosphatesPhosphatidylinositolsPhosphoric Monoester HydrolasesXenopusphosphatidylinositol 3,4,5-triphosphatePhosphatidylinositol PhosphatesPhosphatidylinositolsphosphoinositide-3,4-bisphosphatePhosphoric Monoester Hydrolasesvoltage-sensor-containing phosphatase, Ciona intestinalis

Identifiers

PMID29695412
PMCPMC5940254

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.