Evidence map›Paper›PMID 29695046›Full record

ArticleBiosensors2018

Laser Scribed Graphene Biosensor for Detection of Biogenic Amines in Food Samples Using Locally Sourced Materials.

Diana C Vanegas, Laksmi Patiño, Connie Mendez, Daniela Alves de Oliveira, Alba M Torres, Carmen L Gomes, Eric S McLamore

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 116 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Diana C VanegasDepartment of Food Engineering, Universidad del Valle, Cali 760032, Colombia. vanegas.diana@correounivalle.edu.co.
Laksmi PatiñoDepartment of Food Engineering, Universidad del Valle, Cali 760032, Colombia. laksmi.patino@correounivalle.edu.co.
Connie MendezDepartment of Food Engineering, Universidad del Valle, Cali 760032, Colombia. connie.mendez@correounivalle.edu.co.
Daniela Alves de OliveiraDepartment of Biological and Agricultural Engineering, Texas A&M University, College Station, TX 77843, USA. daoliveira@tamu.edu.
Alba M TorresDepartment of Biology, Universidad del Valle, Cali 760032, Colombia. albamarina.torres@gmail.com.
Carmen L GomesDepartment of Mechanical Engineering, Iowa State University, Ames, IA 50011, USA. carmen@iastate.edu.ORCID 0000-0003-0095-6478
Eric S McLamoreDepartment of Agricultural and Biological Engineering, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL 32611, USA. emclamore@ufl.edu.ORCID 0000-0002-1662-7372
Universidad del Valle · COIowa State University · USTexas A&M University · USUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In foods, high levels of biogenic amines (BA) are the result of microbial metabolism that could be affected by temperatures and storage conditions. Thus, the level of BA is commonly used as an indicator of food safety and quality. This manuscript outlines the development of laser scribed graphene electrodes, with locally sourced materials, for reagent-free food safety biosensing. To fabricate the biosensors, the graphene surface was functionalized with copper microparticles and diamine oxidase, purchased from a local supermarket; and then compared to biosensors fabricated with analytical grade materials. The amperometric biosensor exhibits good electrochemical performance, with an average histamine sensitivity of 23.3 µA/mM, a lower detection limit of 11.6 µM, and a response time of 7.3 s, showing similar performance to biosensors constructed from analytical grade materials. We demonstrated the application of the biosensor by testing total BA concentration in fish paste samples subjected to fermentation with lactic acid bacteria. Biogenic amines concentrations prior to lactic acid fermentation were below the detection limit of the biosensor, while concentration after fermentation was 19.24 ± 8.21 mg histamine/kg, confirming that the sensor was selective in a complex food matrix. The low-cost, rapid, and accurate device is a promising tool for biogenic amine estimation in food samples, particularly in situations where standard laboratory techniques are unavailable, or are cost prohibitive. This biosensor can be used for screening food samples, potentially limiting food waste, while reducing chances of foodborne outbreaks.

Indexed as

Amine Oxidase (Copper-Containing)Biogenic AminesBiosensing TechniquesFood AnalysisGraphiteHumansAmine Oxidase (Copper-Containing)Biogenic AminesGraphitebiogenic aminesdiamine oxidasedisposable sensorfood qualitylaser scribed grapheneplanetary healthrisk assessment

Identifiers

PMID29695046
PMCPMC6023090
OpenAlexW2799870520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.