Evidence map›Paper›PMID 29694854›Full record

ArticleFree radical biology & medicine2018

S-nitrosoglutathione reductase (GSNOR) inhibitor as an immune modulator in experimental autoimmune encephalomyelitis.

Nishant Saxena, Jeseong Won, Seungho Choi, Avtar K Singh, Inderjit Singh

Abstract read
In one paragraph

Article in Free radical biology & medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nishant SaxenaDepartment of Pediatrics, Medical University of South Carolina, Charleston, SC, USA.
Jeseong WonDepartment of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, USA. Electronic address: wonj@musc.edu.
Seungho ChoiDepartment of Pediatrics, Medical University of South Carolina, Charleston, SC, USA.
Avtar K SinghDepartment of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, USA; Pathology and Laboratory Medicine Service, Ralph H. Johnson Veterans Administration Medical Center, Charleston, SC, USA.
Inderjit SinghDepartment of Pediatrics, Medical University of South Carolina, Charleston, SC, USA; Research Service, Ralph H. Johnson Veterans Administration Medical Center, Charleston, SC, USA. Electronic address: singhi@musc.edu.
Medical University of South Carolina · USRalph H. Johnson VA Medical Center · US

Funding

CYTOKINES IN GLIAL CELLS AND EAE BRAINR01NS037766 · NINDS · UNIVERSITY OF NEVADA RENO · PI SINGH, INDERJIT · 1998 to 2019
$5.9M
Immunomodulation and Neuroprotection in Multiple SclerosisI01BX002829 · VA · RALPH H JOHNSON VA MEDICAL CENTER · PI SINGH, INDERJIT · 2015 to 2025
–
BLRD VA I01 BX002829NINDS NIH HHS R01 NS037766
6 · The paper itself

Abstract

We previously reported that S-nitrosoglutathione (GSNO), an endogenous nitric oxide carrier, attenuated T

Indexed as

Disease Models, AnimalAlcohol DehydrogenaseAnimalsBenzamidesCD4-Positive T-LymphocytesEncephalomyelitis, Autoimmune, ExperimentalFemaleMiceMice, Inbred C57BLProtein SPyrrolesTh1 CellsT-Lymphocytes, RegulatoryTyrosine3-nitrotyrosineAdh5 protein, mouseAlcohol DehydrogenaseBenzamidesN6022Protein SPyrrolesTyrosineEAEGSNOGSNOR inhibitorImmue modulationMultiple sclerosisT helper lymphocytes

Identifiers

PMID29694854
PMCPMC6083447
OpenAlexW2799342171

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.