ReviewEinstein (Sao Paulo, Brazil)2018
Chemotherapy protocols and incidence of oral mucositis. An integrative review.
Review in Einstein (Sao Paulo, Brazil), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 3 syntheses or guidelines pooled it, 110 citations in OpenAlex.
- Is photobiomodulation an effective preventive strategy for oral mucositis in patients with hematologic diseases undergoing chemotherapy?: A systematic review of randomized controlled trials.Lasers in medical science · 2026Pooled it
- Predictive models for chemotherapy-induced oral mucositis: a systematic review.Frontiers in oncology · 2025Pooled it
- Probiotic Supplements on Oncology Patients' Treatment-Related Side Effects: A Systematic Review of Randomized Controlled Trials.International journal of environmental research and public health · 2021Pooled it
- Multi-institutional, randomized, controlled trial to assess the efficacy and tolerability of a reusable, self-contained cryotherapy delivery device.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Trial
- Photobiomodulation preconditioning for oral mucositis prevention and quality of life improvement in chemotherapy patients: a randomized clinical trial.BMC oral health · 2025Trial
- Rebamipide gargle and benzydamine gargle in prevention and management of chemo-radiotherapy and radiotherapy-induced oral mucositis in head and neck cancer patients (randomized clinical trial).BMC oral health · 2024Trial
- Potential therapeutic effects of different mouthwashes for alleviation and treatment of oral complications of 5-fluorouracil-based chemotherapy in patients with colon cancer.European journal of hospital pharmacy : science and practice · 2023Trial
- A randomized controlled trial of manual versus powered tooth brushing during haematopoietic stem cell transplantation.Oral diseases · 2022Trial
- The Impact of Cancer Treatment On Oral Structures and the Facial Part of the Skull - Implications for Prosthetic Treatment and Oncological Risk.Current oncology reports · 2026Review
- Exploring the Nutraceutical Potential ofFood science & nutrition · 2026Review
- An economic analysis of Chemo MouthpieceJournal of comparative effectiveness research · 2026Article
- Mediating Role of Dyadic Coping Between Social Support and Oral Frailty Cross-Sectional Study of Elderly Ovarian Cancer Patients in China.International journal of women's health · 2026Article
- Development and validation of a nomogram prediction model for oral frailty in community-dwelling older adults.Frontiers in public health · 2026Article
- Review
- Micro and Nano Drug Delivery Systems for the Treatment of Oral Mucositis: A Review.Pharmaceutics · 2025Review
- Oral frailty and its influencing factors in patients with cancer undergoing chemotherapy: a cross-sectional study.BMC oral health · 2025Article
- Incidence of oral manifestations in hematological malignancy patients undergoing chemotherapy: prospective cohort study.Medicina oral, patologia oral y cirugia bucal · 2025Article
- Protective effect of adenosine triphosphate against cisplatin-induced necrotic and degenerative oral mucositis in rats.Journal of applied oral science : revista FOB · 2025Article
- Evaluation of the Incidence and Stage of Oral Mucositis in Patients Undergoing Hematopoietic Stem Cell Transplantation: A Retrospective Study.Florence Nightingale journal of nursing · 2024Article
- Cold Atmospheric Pressure Plasma May Prevent Oral Mucositis-Related Candidemia in Chemotherapy-Treated Rats.International journal of molecular sciences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review aimed to analyze the scientific production on severity of oral mucositis as an adverse effect of chemotherapy. To this end, we performed a search at PubMed databases combining the keywords "oral mucositis" and "chemotherapy protocol". To describe the investigation, the following variables were considered: journal, year/place, study design, sample, protocol used and incidence of oral mucositis. A total of 547 articles were retrieved, of which 26 were selected. Out of these 26, only 2 reported severity of oral mucositis; the others only reported the presence of the condition. Protocols for treating different types of carcinoma were evaluated in 16 (61.53%) studies, for hematological malignancies in 6 (23.07%), and for hematopoietic stem cell transplantation in 4 (15.4%). Protocols for hematopoietic stem cell transplantation entail a high risk for oral mucositis, just as chemotherapy with cytarabine and high-dose 5-fluorouracil, alkylating agents and platinumbased compounds. To provide the best prevention and treatment for oral mucositis, it is essential to know the chemotherapy protocols used and their effects on the oral cavity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.