ArticleThe British journal of radiology2018
Nausea and vomiting after exposure to non-ionic contrast media: incidence and risk factors focusing on preparatory fasting.
Article in The British journal of radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Fasting Before Cardiac Catheterization: Still Necessary? A Systematic Review and Meta-Analysis of Randomized Clinical Trials.Journal of the American Heart Association · 2025Pooled it
- Effects of Fasting versus Non-Fasting on Emetic Complications in Radiological Examinations Using Intravascular Non-Ionic Iodinated Contrast Media: A Systematic Review and Meta-Analysis.Korean journal of radiology · 2023Pooled it
- Fasting before contrast-enhanced CT and the incidence of acute adverse reactions: a single-center randomized clinical trial.Insights into imaging · 2024Article
- Factors influencing the safety of outpatient coronary CT angiography: a clinical registry study.BMJ open · 2022Article
- Change the preprocedural fasting policy for contrast-enhanced CT: results of 127,200 cases.Insights into imaging · 2022Article
- Preparative Fasting Orders for Medical/Surgical Interventions and Imaging Studies: Time to Review and Revise!Current gastroenterology reports · 2022Review
- Oral hydration as a safe prophylactic measure to prevent post-contrast acute kidney injury in oncologic patients with chronic kidney disease (IIIb) referred for contrast-enhanced computed tomography: subanalysis of the oncological group of the NICIR study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Preprocedural fasting for contrast-enhanced CT: when experience meets evidence.Insights into imaging · 2021Review
- The effect of abolishing instructions to fast prior to contrast-enhanced CT on the incidence of acute adverse reactions.Insights into imaging · 2020Article
- Incidence and Risk Factors of Nausea and Vomiting after Exposure to Low-Osmolality Iodinated Contrast Media in Children: A Focus on Preparative Fasting.Korean journal of radiology · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo prospectively evaluate the incidence of nausea and vomiting after exposure to non-ionic iodinated contrast media (ICM), and to identify potential risk factors, with a focus on fasting duration for solid food and fluids, separately.
methodsFrom January to March 2017, 1175 patients (605 males, 570 females; median age, 60 years; range, 20-91 years) undergoing ICM-enhanced CT were included in this study. Patients received instructions for a 6 h preparatory fast from solid food. Nausea and vomiting after ICM exposure were assessed on a 3-point scale (mild, moderate, severe). Patients' characteristics and the fasting duration were evaluated to identify risk factors using logistic regression analysis.
resultsOf the 1175 patients, 34 [2.9%; 95% confidence interval (CI) (2.0-4.0)] experienced mild nausea. No patients experienced vomiting [95% CI (0.0000-0.0005)]. 1173 (99.8%) carried out a 6 h fast, and the median fasting durations were 14 h for solid food (interquartile range, 12.5-15.5 h) and 11 h for fluid (interquartile range, 0-13.5 h), respectively. Fasting durations for solid food and fluids were not associated with nausea on univariate regression analyses (p = 0.282-1.000 and 0.146-1.000, respectively). Multivariate regression analysis revealed that a history of drug hypersensitivity [odds ratio = 4.33; 95% CI (1.85-17.52); p = 0.039] was independent risk factors for nausea, whereas iobitridol was less nauseous [odds ratio = 0.32; 95% CI (0.11-0.90); p = 0.032].
conclusionMild nausea occurred in 2.9% of patients and none vomited in our study population with a 6 h preparatory fast from solid food. Many patients underwent excessive fasting for fluids as well as solid food and their fasting durations were not associated with nausea. Advances in knowledge: We firstly evaluated fasting durations for solid food and fluids, and their impacts on vomiting or nausea after ICM exposure with an instruction of 6 h preparatory fast for solid food: many patients underwent excessive fasting for fluids and the fasting duration was unrelated to nausea.
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