ArticleLab on a chip2018
"Dip-and-read" paper-based analytical devices using distance-based detection with color screening.
Article in Lab on a chip, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- CRISPR-Programmable Nanoparticle Transport in Salt-Gated Porous Media for Visual DNA Detection.Chemical engineering journal (Lausanne, Switzerland : 1996) · 2026Article
- Vertical-flow tearable paper-tape rolls for scalable multiplexed point-of-care nucleic acid testing.Microsystems & nanoengineering · 2026Article
- Quencher-free CRISPR-based molecular detection using an amphiphilic DNA fluorescence probe.Biosensors & bioelectronics · 2025Article
- Paper-based analytical devices for point-of-need applications.Mikrochimica acta · 2023Review
- Article
- Sustainable Copper Electrochemical Stripping onto a Paper-Based Substrate for Clinical Application.ACS measurement science au · 2022Article
- Recent Developments in Microfluidic Paper-based Analytical Devices for Pharmaceutical Analysis.Current topics in medicinal chemistry · 2022Article
- Microfluidic Paper-based Device for Medicinal Diagnosis.Current topics in medicinal chemistry · 2022Article
- Quantitative Point-of-Care Colorimetric Assay Modeling Using a Handheld Colorimeter.ACS omega · 2021Article
- Strategies for the detection of target analytes using microfluidic paper-based analytical devices.Analytical and bioanalytical chemistry · 2021Review
- A Simple Distance Paper-Based Analytical Device for the Screening of Lead in Food Matrices.Biosensors · 2021Article
- Flow-based System: A Highly Efficient Tool Speeds Up Data Production and Improves Analytical Performance.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2021Article
- Open software platform for automated analysis of paper-based microfluidic devices.Scientific reports · 2020Article
- Sensitive distance-based paper-based quantification of mercury ions using carbon nanodots and heating-based preconcentration.RSC advances · 2020Article
- Distance and Microsphere Aggregation-Based DNA Detection in a Paper-Based Microfluidic Device.SLAS technology · 2020Article
- Graphene oxide nanosheets coupled with paper microfluidics for enhanced on-site airborne trace metal detection.Microsystems & nanoengineering · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
An improved paper-based analytical device (PAD) using color screening to enhance device performance is described. Current detection methods for PADs relying on the distance-based signalling motif can be slow due to the assay time being limited by capillary flow rates that wick fluid through the detection zone. For traditional distance-based detection motifs, analysis can take up to 45 min for a channel length of 5 cm. By using a color screening method, quantification with a distance-based PAD can be achieved in minutes through a "dip-and-read" approach. A colorimetric indicator line deposited onto a paper substrate using inkjet-printing undergoes a concentration-dependent colorimetric response for a given analyte. This color intensity-based response has been converted to a distance-based signal by overlaying a color filter with a continuous color intensity gradient matching the color of the developed indicator line. As a proof-of-concept, Ni quantification in welding fume was performed as a model assay. The results of multiple independent user testing gave mean absolute percentage error and average relative standard deviations of 10.5% and 11.2% respectively, which were an improvement over analysis based on simple visual color comparison with a read guide (12.2%, 14.9%). In addition to the analytical performance comparison, an interference study and a shelf life investigation were performed to further demonstrate practical utility. The developed system demonstrates an alternative detection approach for distance-based PADs enabling fast (∼10 min), quantitative, and straightforward assays.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.