Evidence map›Paper›PMID 29693564›Full record

ReviewNutrients2018

Cerebral Blood Flow Measurements in Adults: A Review on the Effects of Dietary Factors and Exercise.

Peter J Joris, Ronald P Mensink, Tanja C Adam, Thomas T Liu

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07177781 (Longer-term Effects of Wild Blueberry Consumption on Brain Function in Older Men and Women), which is not on this map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07177781 narecruitingnot on this mapstarted 2024, after this paper: background citation

Longer-term Effects of Wild Blueberry Consumption on Brain Function in Older Men and Women

TypeinterventionalSponsorMaastricht University Medical CenterRan2024 to 2026Enrolled36ConditionsBrain Insulin-sensitivity, Brain Vascular Function, Cerebral Blood FlowArmsWild blueberry powder
3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it, 126 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  5. Trial
  6. Hesperetin-7-Nutrients · 2023
    Trial
  7. Trial
  8. Trial
  9. Trial
  10. Taekwondo Enhances Cognitive Function as a Result of Increased Neurotrophic Growth Factors in Elderly Women.International journal of environmental research and public health · 2019
    Trial
  11. Endocrine modulation of cortical and retinal baseline perfusion across the menstrual cycle.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
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  18. Review
  19. The U.S. POINTER neurovascular ancillary study: Study design and methods.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Peter J JorisDepartment of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, 6200 MD Maastricht, The Netherlands. p.joris@maastrichtuniversity.nl.ORCID 0000-0001-6852-5776
Ronald P MensinkDepartment of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, 6200 MD Maastricht, The Netherlands. r.mensink@maastrichtuniversity.nl.
Tanja C AdamDepartment of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, 6200 MD Maastricht, The Netherlands. t.adam@maastrichtuniversity.nl.
Thomas T LiuCenter for Functional Magnetic Resonance Imaging (MRI), University of California San Diego, La Jolla, CA 92093-0677, USA. ttliu@ucsd.edu.ORCID 0000-0002-1978-7486
University Medical Center · USUniversity of California San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Improving cerebrovascular function may be a key mechanism whereby a healthy lifestyle, of which a healthy diet combined with increased physical activity levels is a cornerstone, protects against cognitive impairments. In this respect, effects on cerebral blood flow (CBF)—a sensitive physiological marker of cerebrovascular function—are of major interest. This review summarizes the impact of specific dietary determinants and physical exercise on CBF in adults and discusses the relation between these effects with potential changes in cognitive function. A limited number of randomized controlled trials have already demonstrated the beneficial effects of an acute intake of nitrate and polyphenols on CBF, but evidence for a relationship between these effects as well as improvements in cognitive functioning is limited. Moreover, long-term trans-resveratrol supplementation has been shown to increase CBF in populations at increased risk of accelerated cognitive decline. Long-term supplementation of

Indexed as

Cerebrovascular CirculationCognitionDietDietary SupplementsExerciseAlcohol DrinkingBrainCaffeineCognitive AgingFatty Acids, Omega-3HumansResveratrolStilbenesCaffeineFatty Acids, Omega-3ResveratrolStilbenesarterial spin labelingbrain healthcerebral blood flowcognitive functiondietexercisemagnetic resonance imagingvascular function

Identifiers

PMID29693564
PMCPMC5986410
OpenAlexW2801876116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.