Evidence map›Paper›PMID 29692996›Full record

ArticleERJ open research2018

Predicting pulmonary tuberculosis in immigrants: a retrospective cohort study.

Courtney Heffernan, Alexander Doroshenko, Mary Lou Egedahl, James Barrie, Ambikaipakan Senthilselvan, Richard Long

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Two Clinical Prediction Tools to Improve Tuberculosis Contact Investigation.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Courtney HeffernanTuberculosis Program Evaluation and Research Unit, Dept of Medicine, University of Alberta, Edmonton, AB, Canada.ORCID 0000-0003-1241-7201
Alexander DoroshenkoTuberculosis Program Evaluation and Research Unit, Dept of Medicine, University of Alberta, Edmonton, AB, Canada.
Mary Lou EgedahlTuberculosis Program Evaluation and Research Unit, Dept of Medicine, University of Alberta, Edmonton, AB, Canada.
James BarrieDept of Radiology, University of Alberta, Edmonton, AB, Canada.
Ambikaipakan SenthilselvanSchool of Public Health, University of Alberta, Edmonton, AB, Canada.
Richard LongTuberculosis Program Evaluation and Research Unit, Dept of Medicine, University of Alberta, Edmonton, AB, Canada.
University of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our objective was to investigate whether pulmonary tuberculosis (PTB) can be predicted from features of a targeted medical history and basic laboratory investigations in immigrants. A retrospective cohort of 391 foreign-born adults referred to the Edmonton Tuberculosis Clinic (Edmonton, AB, Canada) was studied using multiple logistic regression analysis to predict PTB. Seven characteristics of disease were used as explanatory variables. Cross-validation assessed performance. Each predictor was tested on two outcomes: "culture-positive" and "smear-positive". Receiver operating characteristic (ROC) curves were generated and the area under the ROC curve (AUC) was quantified. Symptoms, subacute duration of symptoms, risk factors for reactivation of latent TB infection and anaemia were all associated with a positive culture (adjusted OR 1.79, 2.24, 1.72 and 2.28, respectively; p<0.05). Symptoms, inappropriate prescription of broad-spectrum antibiotics and a "typical" chest radiograph were associated with smear-positive PTB (adjusted OR 2.91, 1.55 and 12.34, respectively; p<0.05). ROC curve analysis was used to test

Identifiers

PMID29692996
PMCPMC5909047
OpenAlexW2801756079

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.