Evidence map›Paper›PMID 29692978›Full record

ArticleInternational journal of pharmaceutical investigation

Effect of local application of curcumin and ornidazole gel in chronic periodontitis patients.

P L Ravishankar, Y Pradeep Kumar, E N Anila, Priyankar Chakraborty, Maharshi Malakar, R Mahalakshmi

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of pharmaceutical investigation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 38 citations in OpenAlex.

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  7. Application of injectable hydrogels in the treatment of periodontitis.Frontiers in bioengineering and biotechnology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

P L RavishankarDepartment of Periodontics, SRM Kattankulathur Dental College, Kanchipuram, Tamil Nadu, India.
Y Pradeep KumarDepartment of Periodontics, SRM Kattankulathur Dental College, Kanchipuram, Tamil Nadu, India.
E N AnilaDepartment of Periodontics, SRM Kattankulathur Dental College, Kanchipuram, Tamil Nadu, India.
Priyankar ChakrabortyDepartment of Periodontics, SRM Kattankulathur Dental College, Kanchipuram, Tamil Nadu, India.
Maharshi MalakarDepartment of Periodontics, SRM Kattankulathur Dental College, Kanchipuram, Tamil Nadu, India.
R MahalakshmiDepartment of Periodontics, SRM Kattankulathur Dental College, Kanchipuram, Tamil Nadu, India.
SRM Dental College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of this study is to evaluate the comparative effect of curcumin and ornidazole in treating chronic periodontitis. MATERIALS AND

methodsTwenty individuals of both sexes aged between 27 and 53 years diagnosed with chronic periodontitis and having pocket depths >5 mm bilaterally were selected for this study, in a split-mouth design. Examination of plaque index, probing pocket depth, and clinical attachment level was measured for each patient. The patients received a complete prophylaxis including scaling and root planing after which, both test gels were injected into the two experimental sites chosen, that had probing depth (PD) >5 mm and were located in symmetric quadrants. Pocket PD, clinical attachment loss, and plaque index were recorded at days 0 and 30.

resultsAt 1-month evaluation, curcumin group showed a significant decrease in pocket PD, plaque index, and clinical attachment loss when compared to the ornidazole group.

conclusionThe results show a more favorable outcome with curcumin than ornidazole gel, thus curcumin can be used as an adjunct to nonsurgical periodontal therapy.

Indexed as

Curcuminlocal drug deliveryornidazole

Identifiers

PMID29692978
PMCPMC5903023
OpenAlexW2796280705

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.