Evidence map›Paper›PMID 29692864›Full record

ReviewChinese medicine2018

Techniques for extraction and isolation of natural products: a comprehensive review.

Qing-Wen Zhang, Li-Gen Lin, Wen-Cai Ye

Open access · goldAbstract readReview
In one paragraph

Review in Chinese medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 518 papers.

0numbers the graph read from it
0cells of the map it votes in
518citing papers in PubMed
42.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

518 citing papers in PubMed, 2,126 citations in OpenAlex.

  1. Trial
  2. Review
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  7. Review
  8. Article
  9. Article
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  12. Green-synthesized metal oxide nanoparticles enhance the antibacterial activity of Portulaca oleracea through foliar nano-elicitation.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  13. Microwave and solvent extraction ofFood chemistry: X · 2026
    Article
  14. Review
  15. Article
  16. Papaya (Molecules (Basel, Switzerland) · 2026
    Article
  17. Life (Basel, Switzerland) · 2026
    Article
  18. Article
  19. Article
  20. Review

458 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Qing-Wen ZhangState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, People's Republic of China.ORCID 0000-0001-9628-296X
Li-Gen LinState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, People's Republic of China.
Wen-Cai Ye2Institute of Traditional Chinese Medicine & Natural Products, and Guangdong Provincial Engineering Research Center for Modernization of TCM, College of Pharmacy, Jinan University, Guangzhou, 510632 People's Republic of China.
University of Macau · MOJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural medicines were the only option for the prevention and treatment of human diseases for thousands of years. Natural products are important sources for drug development. The amounts of bioactive natural products in natural medicines are always fairly low. Today, it is very crucial to develop effective and selective methods for the extraction and isolation of those bioactive natural products. This paper intends to provide a comprehensive view of a variety of methods used in the extraction and isolation of natural products. This paper also presents the advantage, disadvantage and practical examples of conventional and modern techniques involved in natural products research.

Indexed as

ChromatographyExtractionIsolationNatural medicineNatural productsPhytochemical investigation

Identifiers

PMID29692864
PMCPMC5905184
OpenAlexW2802621137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.