Evidence map›Paper›PMID 29692860›Full record

ArticleAnnals of general psychiatry2018

The long-term outcome of patients with heroin use disorder/dual disorder (chronic psychosis) after admission to enhanced methadone maintenance.

Angelo G I Maremmani, Alessandro Pallucchini, Luca Rovai, Silvia Bacciardi, Vincenza Spera, Marco Maiello, Giulio Perugi, Icro Maremmani

Open access · goldAbstract read
In one paragraph

Article in Annals of general psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. The Prevalence and Psychosocial Correlates of Ketum (Healthcare (Basel, Switzerland) · 2022
    Article
  2. Article
  3. Article
  4. Article
  5. What we have learned from the Methadone Maintenance Treatment of Dual Disorder Heroin Use Disorder patients.International journal of environmental research and public health · 2019
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Angelo G I MaremmaniDepartment of Psychiatry, North-Western Tuscany Local Health Unit, Versilian Zone, Viareggio, Italy.
Alessandro Pallucchini4School of Psychiatry, University of Pisa, Pisa, Italy.
Luca RovaiDepartment of Psychiatry, North-Western Tuscany Local Health Unit, Apuan Zone, Massa, Italy.
Silvia Bacciardi4School of Psychiatry, University of Pisa, Pisa, Italy.
Vincenza Spera4School of Psychiatry, University of Pisa, Pisa, Italy.
Marco Maiello4School of Psychiatry, University of Pisa, Pisa, Italy.
Giulio Perugi6Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Icro MaremmaniAU-CNS, Association for the Application of Neuroscientific Knowledge to Social Aims, Pietrasanta, Lucca, Italy.
University of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOver-standard methadone doses are generally needed in the treatment of heroin use disorder (HUD) patients that display concomitant high-severity psychopathological symptomatology. A flexible dosing regimen may lead to higher retention rates in dual disorder (DD), as we demonstrated in bipolar 1 HUD patients, leading to outcomes that are as satisfactory as those of HUD patients without high-severity psychopathological symptomatology.

objectiveThis study aimed to compare the long-term outcomes of treatment-resistant chronic psychosis HUD patients (PSY-HUD) with those of peers without dual disorder (HUD).

methods85 HUD patients who also met the criteria for treatment resistance-25 of them affected by chronic psychosis and 60 without DD-were monitored prospectively for up to 8 years while continuing to receive enhanced methadone maintenance treatment.

resultsThe rates of endurance in the treatment of PSY-HUD patients were 36%, compared with 34% for HUD patients (

conclusionsAn enhanced methadone maintenance treatment seems to be equally effective in patients with PSY-HUD and those with HUD.

Indexed as

Chronic psychosisDual disorderHigh-threshold methadone maintenance programmeLong-term outcomeMethadone maintenance

Identifiers

PMID29692860
PMCPMC5905164
OpenAlexW2803111910

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.