ReviewDrugs in context2018
Emollient treatment of atopic dermatitis: latest evidence and clinical considerations.
Review in Drugs in context, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03701971 (Randomized Prospective Open-label Study Evaluating the Benefit of Music Therapy on Pruritus in Patients With Pruritic Dermatitis), which is not on this map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Prospective Open-label Study Evaluating the Benefit of Music Therapy on Pruritus in Patients With Pruritic Dermatitis
Who cites it
35 citing papers in PubMed, 98 citations in OpenAlex.
- A randomized clinical study on the effects of emollient use on the developing infant skin microbiome and metabolome.Experimental dermatology · 2023Trial
- A Clinical Investigation of the Performance and Safety of EpadermClinical, cosmetic and investigational dermatology · 2021Trial
- A randomized half-body, double blind, controlled trial on the effects of a pH-modified moisturizer vs. standard moisturizer in mild to moderate atopic dermatitis.Anais brasileiros de dermatologiaTrial
- Molecular Targets in Modern Cosmetic Science.Molecules (Basel, Switzerland) · 2026Review
- Review
- Noninvasive assessment of skin barrier function: evaluating ceramide-based moisturizer using confocal Raman spectroscopy.Journal of biomedical optics · 2025Article
- Update on the Research of an Emulgel for the Effective Treatment of Atopic Dermatitis: Clinical Investigation in Children.Gels (Basel, Switzerland) · 2025Article
- Unlocking the Rich Potential of a Soft Gel-Cream Enriched with Royal Jelly for Topical Use.Gels (Basel, Switzerland) · 2025Article
- A systematic review of guidelines for the management of atopic dermatitis in children.The World Allergy Organization journal · 2024Review
- Efficacy of a Multi-lamellar Emulsion Containing a Synthetic Sphingosine Kinase 1 Activator and Pseudoceramide in Patients with Atopic Dermatitis: A Randomized Controlled Trial.Dermatology and therapy · 2024Article
- Treatment of Atopic Dermatitis in Children.Cureus · 2024Review
- Biologic and Small Molecule Therapy in Atopic Dermatitis.Biomedicines · 2024Review
- Palmitoylethanolamide-Incorporated Elastic Nano-Liposomes for Enhanced Transdermal Delivery and Anti-Inflammation.Pharmaceutics · 2024Article
- Article
- Resveratrol and Its Derivatives in Inflammatory Skin Disorders-Atopic Dermatitis and Psoriasis: A Review.Antioxidants (Basel, Switzerland) · 2023Review
- Hand Eczema in the Polish Female Population.Journal of clinical medicine · 2023Article
- Design and Evaluation of Dissolvable Microneedles for Treating Atopic Dermatitis.Pharmaceutics · 2023Article
- Link between the skin and autism spectrum disorder.Frontiers in psychiatry · 2023Article
- Extract of Wheatgrass and Aronia Mixture Ameliorates Atopic Dermatitis-Related Symptoms by Suppressing Inflammatory Response and Oxidative Stress In Vitro and In Vivo.Antioxidants (Basel, Switzerland) · 2022Article
- The link between cutaneous inflammation and cognitive impairment.Journal of the European Academy of Dermatology and Venereology : JEADV · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo review current classes of emollients in the market, their clinical efficacy in atopic dermatitis (AD) and considerations for choice of an emollient.
methodsPubMed Clinical Queries under Clinical Study Categories (with Category limited to Therapy and Scope limited to Narrow) and Systematic Reviews were used as the search engine. Keywords of 'emollient or moisturizer' and 'atopic dermatitis' were used. OVERVIEW OF
findingsUsing the keywords of 'emollient' and 'atopic dermatitis', there were 105 and 36 hits under Clinical Study Categories (with Category limited to Therapy and Scope limited to Narrow) and Systematic Reviews, respectively. Plant-derived products, animal products and special ingredients were discussed. Selected proprietary products were tabulated.
conclusionsA number of proprietary emollients have undergone trials with clinical data available on PubMed-indexed journals. Most moisturizers showed some beneficial effects, but there was generally no evidence that one moisturizer is superior to another. Choosing an appropriate emollient for AD patients would improve acceptability and adherence for emollient treatment. Physician's recommendation is the primary consideration for patients when selecting a moisturizer/emollient; therefore, doctors should provide evidence-based information about these emollients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.