ArticleIranian endodontic journal2018
A Review on Triple Antibiotic Paste as a Suitable Material Used in Regenerative Endodontics.
Article in Iranian endodontic journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05291195 (Treatment of Chronic Periapical Periodontitis of Young Permanent Teeth by Means of Three Adjuvant Treatment Approaches), which is not on this map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Treatment of Chronic Periapical Periodontitis of Young Permanent Teeth by Means of Three Adjuvant Treatment Approaches: A Prospective Comparative Microbiological and Clinical Study
Who cites it
36 citing papers in PubMed, 61 citations in OpenAlex.
- Article
- Effect of Chitosan and bioactive glass nanomaterials as intracanal medicaments on TGF-β1 release from intraradicular dentin.BMC oral health · 2025Article
- Regenerative Endodontic Treatment in an Immature Permanent Tooth With Necrotic Pulp and Periradicular Lesion.Clinical case reports · 2025Article
- Evaluation of Cytotoxicity of Premixed Triple Antibiotic Paste on Stem Cells of Apical Papilla Using MTT Assay: AnInternational journal of clinical pediatric dentistry · 2025Article
- Cytotoxicity of Different Concentrations of Silver Nanoparticles and Calcium Hydroxide for MC3T3-E1 Preosteoblast Cell Line.Clinical and experimental dental research · 2025Article
- Effect of Various Disinfection Protocols on Endodontic Biofilm and Growth Factors Release from Radicular Dentin: An In Vitro Study.European endodontic journal · 2025Article
- Antibiofilm efficacy of a calcium silicate-based intracanal medicament against Fusobacterium nucleatum strains.Scientific reports · 2024Article
- Triple Antibiotic Paste: A Game Changer in Endodontics.Journal of pharmacy & bioallied sciences · 2024Review
- A Comparative Evaluation of Herbal Extracts and Triple Antibiotic Paste as Intracanal Medicament againstInternational journal of clinical pediatric dentistry · 2024Article
- The Efficacy of Different Antibiotic Compounds in Regenerative Treatment of Immature Necrotic Teeth.Frontiers in dentistry · 2024Article
- Regeneration of immature incisor using platelet rich fibrin: report of a novel clinical application.BMC oral health · 2023Article
- Healing of Large Endodontic Lesions Using Long-Term Application of a New Combination of Triple Antibiotics: A Series of Cases.Case reports in dentistry · 2023Article
- A Scoping Review of Highly Cited Published Articles in the Iranian Endodontic Journal: A Reflection of Trends in Endodontic Research.Iranian endodontic journal · 2023Article
- Long-term treatment of dentine with triple antibiotic paste promotes stem cell viability and attachment.Journal of Taibah University Medical Sciences · 2022Article
- Efficacy of Ciprofloxacin, Metronidazole and Minocycline in Ordered Mesoporous Silica againstMaterials (Basel, Switzerland) · 2022Article
- Regenerative Endodontics Success Factors and their Overall Effectiveness: An Umbrella Review.Iranian endodontic journal · 2022Review
- Evaluation of Antibacterial Effects of Cold Atmospheric Plasma, Calcium Hydroxide, and Triple Antibiotic Paste onJournal of lasers in medical sciences · 2022Article
- Regenerative Endodontic Treatment of a Traumatized Immature Necrotic Permanent Incisor: A Case Report.Iranian endodontic journal · 2022Article
- Photodynamic Therapy in Endodontics: A Helpful Tool to Combat Antibiotic Resistance? A Literature Review.Antibiotics (Basel, Switzerland) · 2021Review
- Antibiotic Mixtures in Noninstrumental Endodontic Treatment of Primary Teeth with Necrotic Pulps: A Systematic Review.International journal of dentistry · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As the root canal system shows different and complicated anatomies, mechanical instrumentation alone has not the ability to provide a bacteria-free environment in root canals. On the other aspect, necrotic tissue remaining can decrease the effects of root canal irrigants and medicaments and also interfere with the adaptation of root canal fillings to dentin. As a result, certain disinfection and irrigation procedures are required to remove the remaining tissues from the root canal area thoroughly and also be able to eliminate the microorganisms. Triple antibiotic paste (TAP) containing metronidazole, ciprofloxacin and minocycline has been proposed as a root canal medicament due to its antimicrobial effects in endodontic regenerative procedures. The purposes of this review were to determine the properties of TAP drugs and to evaluate the efficiency of TAP on the root canal disinfection, in primary and permanent teeth, along with its affection in regeneration/revascularization procedures. The biocompatibility and disadvantages of this medicament were also discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.