Evidence map›Paper›PMID 29692785›Full record

ReviewFrontiers in immunology2018

The Selective Autophagy Receptor Optineurin in Crohn's Disease.

Markus Tschurtschenthaler, Timon Erik Adolph

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Frontiers in immunology · 2022
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Methylomic correlates of autophagy activity in cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2019
    Article
  14. Article
  15. Article
  16. Selective Autophagy and Xenophagy in Infection and Disease.Frontiers in cell and developmental biology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Markus TschurtschenthalerCenter for Translational Cancer Research (TranslaTUM), Technical University of Munich, Munich, Germany.
Timon Erik AdolphDepartment of Medicine I (Gastroenterology, Endocrinology and Metabolism), Medical University Innsbruck, Innsbruck, Austria.
Innsbruck Medical University · ATKlinikum rechts der Isar · DE

Funding

Austrian Science Fund FWF P 29379
6 · The paper itself

Abstract

Autophagy is a pathway that allows cells to target organelles, protein complexes, or invading microorganisms for lysosomal degradation. The specificity of autophagic processes is becoming increasingly recognized and is conferred by selective autophagy receptors such as Optineurin (OPTN). As an autophagy receptor, OPTN controls the clearance of

Indexed as

AnimalsAutophagyCell Cycle ProteinsCrohn DiseaseHumansMembrane Transport ProteinsTranscription Factor TFIIIACell Cycle ProteinsMembrane Transport ProteinsOPTN protein, humanTranscription Factor TFIIIACrohn’s diseaseendoplasmic reticulum stressinflammatory bowel diseaseoptineurinselective autophagy

Identifiers

PMID29692785
PMCPMC5902526
OpenAlexW2796765798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.