ArticleFrontiers in neurology2018
Hierarchical Cluster Analysis of Semicircular Canal and Otolith Deficits in Bilateral Vestibulopathy.
Article in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 30 citations in OpenAlex.
- Prospective cohort study on the predictors of fall risk in 119 patients with bilateral vestibulopathy.PloS one · 2020Trial
- The Need for Vestibular Implants in a Tertiary Referral Ear, Nose, and Throat Center and Its Relation to Hearing Status.The journal of international advanced otology · 2023Article
- Bilateral vestibulopathy: a clinical update and proposed diagnostic algorithm.Frontiers in neurology · 2023Review
- Bilateral vestibulopathy decreases self-motion perception.Journal of neurology · 2022Article
- Patterns of Vestibular Impairment in Bilateral Vestibulopathy and Its Relation to Etiology.Frontiers in neurology · 2022Article
- Acute Unilateral Peripheral Vestibulopathy After COVID-19 Vaccination: Initial Experience in a Tertiary Neurotology Center.Frontiers in neurology · 2022Article
- Rare Disorders of the Vestibular Labyrinth: of Zebras, Chameleons and Wolves in Sheep's Clothing.Laryngo- rhino- otologie · 2021Review
- Paving the Way Toward Distinguishing Fallers From Non-fallers in Bilateral Vestibulopathy: A Wide Pilot Observation.Frontiers in neurology · 2021Article
- The vestibular implant: Opinion statement on implantation criteria for research.Journal of vestibular research : equilibrium & orientation · 2020Review
- Recent advances in idiopathic bilateral vestibulopathy: a literature review.Orphanet journal of rare diseases · 2019Review
- Vestibular evoked myogenic potentials in practice: Methods, pitfalls and clinical applications.Clinical neurophysiology practice · 2019Review
- Decoding the bilateral vestibulopathy spectrum: etiology-based phenotypes, clinical profiles and pathways to implant candidacy.Frontiers in neurologyArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGait imbalance and oscillopsia are frequent complaints of bilateral vestibular loss (BLV). Video-head-impulse testing (vHIT) of all six semicircular canals (SCCs) has demonstrated varying involvement of the different canals. Sparing of anterior-canal function has been linked to aminoglycoside-related vestibulopathy and Menière's disease. We hypothesized that utricular and saccular impairment [assessed by vestibular-evoked myogenic potentials (VEMPs)] may be disease-specific also, possibly facilitating the differential diagnosis.
methodsWe searched our vHIT database (
resultsRates of utricular and saccular loss of function were similar (87.1 vs. 78.2%, DISCUSSION: Hierarchical cluster analysis may help differentiate characteristic patterns of BVL. With a prevalence of ≈80%, utricular and/or saccular impairment is frequent in BVL. The extent of SCC and otolith impairment was disease-dependent, showing most extensive damage in BVL related to inner-ear infection and aminoglycoside-exposure and more selective impairment in Menière's disease. Specifically, assessing utricular function may help in the distinction between aminoglycoside-related BVL and bilateral Menière's disease.
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