Evidence map›Paper›PMID 29692674›Full record

ArticleReproductive medicine and biology2018

Co-expression of the calcitonin receptor gene in the hypothalamic kisspeptin neurons in female rats.

Assadullah, Nahoko Ieda, Narumi Kawai, Hirotaka Ishii, Kunio Ihara, Naoko Inoue, Yoshihisa Uenoyama, Hiroko Tsukamura

Open access · goldAbstract read
In one paragraph

Article in Reproductive medicine and biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Direct evidence that KNDy neurons maintain gonadotropin pulses and folliculogenesis as the GnRH pulse generator.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

AssadullahGraduate School of Bioagricultural Sciences Nagoya University Nagoya Japan.
Nahoko IedaGraduate School of Bioagricultural Sciences Nagoya University Nagoya Japan.
Narumi KawaiGraduate School of Bioagricultural Sciences Nagoya University Nagoya Japan.
Hirotaka IshiiDepartment of Anatomy and Neurobiology Nippon Medical School Tokyo Japan.ORCID 0000-0003-2044-316X
Kunio IharaCenter for Gene Research Nagoya University Nagoya Japan.
Naoko InoueGraduate School of Bioagricultural Sciences Nagoya University Nagoya Japan.
Yoshihisa UenoyamaGraduate School of Bioagricultural Sciences Nagoya University Nagoya Japan.ORCID 0000-0002-8272-2781
Hiroko TsukamuraGraduate School of Bioagricultural Sciences Nagoya University Nagoya Japan.
Nagoya University · JPNippon Medical School Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHypothalamic kisspeptin neurons are considered to play a critical role in regulating mammalian reproduction and integrating humoral and neuronal inputs that control gonadotropin-releasing hormone (GnRH)/gonadotropin release. The present study aimed to investigate the upstream regulator candidates for kisspeptin neurons.

methodsVisualized kisspeptin neurons that were taken from the arcuate nucleus (ARC) of

resultsThe NGS analysis revealed that the

conclusionThe present study suggests that calcitonin receptor signaling could be involved in the regulation of reproductive function through the direct control of the ARC and/or AVPV kisspeptin neurons, and then GnRH/gonadotropin release.

Indexed as

anteroventral periventricular nucleusarcuate nucleuscalcitonin receptorsin situ hybridizationkisspeptin‐1

Identifiers

PMID29692674
PMCPMC5902471
OpenAlexW2793851832

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.