Evidence map›Paper›PMID 29692609›Full record

ReviewInternational journal of nanomedicine2018

Nano-selenium and its nanomedicine applications: a critical review.

Bozena Hosnedlova, Marta Kepinska, Sylvie Skalickova, Carlos Fernandez, Branislav Ruttkay-Nedecky, Qiuming Peng, Mojmir Baron, Magdalena Melcova, Radka Opatrilova, Jarmila Zidkova and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 203 papers.

0numbers the graph read from it
0cells of the map it votes in
203citing papers in PubMed
29.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

203 citing papers in PubMed, 597 citations in OpenAlex.

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  20. Elemental Selenium/Tellurium in Polymer Assemblies: Responsive Innovation.Polymer science & technology (Washington, D.C.) · 2026
    Review

143 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 5 countries.

Bozena HosnedlovaDepartment of Viticulture and Enology, Faculty of Horticulture, Mendel University in Brno, Lednice, Czech Republic.
Marta KepinskaDepartment of Biomedical and Environmental Analyses, Faculty of Pharmacy, Wroclaw Medical University, Wroclaw, Poland.
Sylvie SkalickovaCentral Laboratory, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic.
Carlos FernandezSchool of Pharmacy and Life Sciences, Robert Gordon University, Aberdeen, UK.
Branislav Ruttkay-NedeckyCentral Laboratory, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic.
Qiuming PengState Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao, People's Republic of China.
Mojmir BaronDepartment of Viticulture and Enology, Faculty of Horticulture, Mendel University in Brno, Lednice, Czech Republic.
Magdalena MelcovaDepartment of Biochemistry and Microbiology, University of Chemistry and Technology, Prague, Czech Republic.
Radka OpatrilovaCentral Laboratory, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic.
Jarmila ZidkovaDepartment of Biochemistry and Microbiology, University of Chemistry and Technology, Prague, Czech Republic.
Geir BjørklundCouncil for Nutritional and Environmental Medicine, Rana, Norway.
Jiri SochorDepartment of Viticulture and Enology, Faculty of Horticulture, Mendel University in Brno, Lednice, Czech Republic.
Rene KizekDepartment of Biomedical and Environmental Analyses, Faculty of Pharmacy, Wroclaw Medical University, Wroclaw, Poland.
University of Veterinary Sciences Brno · CZMendel University in Brno · CZUniversity of Chemistry and Technology, Prague · CZRobert Gordon University · GBThe Research Council of Norway · NOWroclaw Medical University · PLYanshan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional supplements of selenium generally have a low degree of absorption and increased toxicity. Therefore, it is imperative to develop innovative systems as transporters of selenium compounds, which would raise the bioavailability of this element and allow its controlled release in the organism. Nanoscale selenium has attracted a great interest as a food additive especially in individuals with selenium deficiency, but also as a therapeutic agent without significant side effects in medicine. This review is focused on the incorporation of nanotechnological applications, in particular exploring the possibilities of a more effective way of administration, especially in selenium-deficient organisms. In addition, this review summarizes the survey of knowledge on selenium nanoparticles, their biological effects in the organism, advantages, absorption mechanisms, and nanotechnological applications for peroral administration.

Indexed as

Administration, OralDrug Delivery SystemsFood AdditivesHumansIntestinal MucosaNanomedicineNanoparticlesNanotechnologySeleniumFood AdditivesSeleniumanticancer effectantimicrobial activitybiomedicinedrug deliverynanoparticlesoxidative stressprotective effect

Identifiers

PMID29692609
PMCPMC5901133
OpenAlexW2796973106

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.