Evidence map›Paper›PMID 29692537›Full record

ArticleThe Indian journal of radiology & imaging

Brown fat necrosis with calcifications in the newborn: Risk factors, radiographic findings, and clinical course.

Eleza T Golden, Paula Dickson, Stephen Simoneaux

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Indian journal of radiology & imaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eleza T GoldenDepartment of Radiology and Imaging Sciences, Children's Healthcare of Atlanta and Emory University, 1405 Clifton Road NE, Atlanta, Georgia 30322.
Paula DicksonDepartment of Radiology and Imaging Sciences, Children's Healthcare of Atlanta and Emory University, 1405 Clifton Road NE, Atlanta, Georgia 30322.
Stephen SimoneauxDepartment of Radiology and Imaging Sciences, Children's Healthcare of Atlanta and Emory University, 1405 Clifton Road NE, Atlanta, Georgia 30322.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the radiographic appearance of subclinical calcified brown fat necrosis and the associated clinical and laboratory findings. MATERIALS AND

methodsPicture Archiving and Communications Sytem (PACS) was searched using keywords "soft tissue calcification" and "chest." The clinical record was searched for prior cardiac surgery, bypass, Extracorporeal Membrane Oxygentation (ECMO) and prostaglandin use. Age when calcifications were first detected, location, resolution, and associated laboratory abnormalities were recorded.

resultsNine patients were identified. None had skin lesions. All patients had congenital heart disease and had experienced cardiac/respiratory arrest and/or severe hypotension 1-6 weeks before soft tissue calcifications occurred. Calcifications resolved by 9 weeks to 5 months in 3 patients. The remaining were either deceased or lacked follow-up imaging. Renal ultrasound was performed in all but 1 patient. Nephrocalcinosis was only seen in 1 patient.

conclusionBrown fat necrosis is subclinical, diagnosed on plain film, and likely self-limited. It occurs in term and preterm infants who have undergone significant systemic stress and carries a poor prognosis.

Indexed as

neonatal imagingNeonatesubcutaneous fat necrosis

Identifiers

PMID29692537
PMCPMC5894305

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.