Evidence map›Paper›PMID 29692196›Full record

ReviewCell transplantation2018

Fighting against Skin Aging: The Way from Bench to Bedside.

Shoubing Zhang, Enkui Duan

2 registry-linked trialsOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cell transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 291 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
291citing papers in PubMed, 3 pooled it
40.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04485091 phase2completednot on this mapstarted 2021, after this paper: background citation

Association of Trichloroacetic Acid Peel With Photobiomodulation in the Treatment of Skin Photoaging of the Hands: a Study Protocol for a Controlled, Randomized, Double-blind Clinical Trial.

TypeinterventionalSponsorUniversity of Nove de JulhoRan2021 to 2022Enrolled42ConditionsSkin AgingArms20% TCM and PBM, 20% TCM and PBM placebo
NCT05986799 naunknown statusnot on this mapstarted 2023, after this paper: background citation

A Randomized, Controlled Trial of Efficacy of Amway Herbal Drink to Improve Skin Anti-aging

TypeinterventionalSponsorAmway (China) R&D CenterRan2023 to 2023Enrolled30ConditionsSkin Laxity, Skin LinesArmsAmway Herbal Drink, Placebo Drink
3 · Its place in the literature

Who cites it

291 citing papers in PubMed, 3 syntheses or guidelines pooled it, 710 citations in OpenAlex.

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  17. LiposomalInternational journal of molecular sciences · 2026
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231 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Shoubing Zhang1 Department of Histology and Embryology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Enkui Duan3 State Key Lab of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Anhui Medical University · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the most voluminous organ of the body that is exposed to the outer environment, the skin suffers from both intrinsic and extrinsic aging factors. Skin aging is characterized by features such as wrinkling, loss of elasticity, laxity, and rough-textured appearance. This aging process is accompanied with phenotypic changes in cutaneous cells as well as structural and functional changes in extracellular matrix components such as collagens and elastin. In this review, we summarize these changes in skin aging, research advances of the molecular mechanisms leading to these changes, and the treatment strategies aimed at preventing or reversing skin aging.

Indexed as

Translational Research, BiomedicalHumansInflammationModels, BiologicalSkin AgingStem Cell TransplantationTelomereextracellular matrixextrinsic agingintrinsic agingskin agingtreatment strategy

Identifiers

PMID29692196
PMCPMC6047276
OpenAlexW2800438504

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.