Evidence map›Paper›PMID 29692194›Full record

ReviewAnnals of the Royal College of Surgeons of England2018

Gastrointestinal manifestations of extramedullary plasmacytoma: a narrative review and illustrative case reports.

J C Glasbey, F Arshad, L M Almond, B Vydianath, A Desai, D Gourevitch, S J Ford

Abstract readCase ReportsReview
In one paragraph

Review in Annals of the Royal College of Surgeons of England, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

J C GlasbeyDepartment of Soft Tissue Sarcoma, Queen Elizabeth Hospital , Birmingham , UK.
F ArshadDepartment of Soft Tissue Sarcoma, Queen Elizabeth Hospital , Birmingham , UK.
L M AlmondDepartment of Soft Tissue Sarcoma, Queen Elizabeth Hospital , Birmingham , UK.
B VydianathDepartment of Histopathology, Queen Elizabeth Hospital , Birmingham , UK.
A DesaiDepartment of Soft Tissue Sarcoma, Queen Elizabeth Hospital , Birmingham , UK.
D GourevitchDepartment of Soft Tissue Sarcoma, Queen Elizabeth Hospital , Birmingham , UK.
S J FordDepartment of Soft Tissue Sarcoma, Queen Elizabeth Hospital , Birmingham , UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Solitary extramedullary plasmacytoma are rare, solid-mass tumours which appear immunophenotypically similar to multiple myeloma. The diagnosis and management of gastrointestinal plasmacytoma is complex and requires multidisciplinary input. This study presents a narrative review of intra-abdominal extramedullary plasmacytoma, illustrated with two case studies. Methods The PubMed database was searched without date restrictions for reports of intra-abdominal extramedullary plasmacytoma to synthesise a narrative review. Electronic records were reviewed at a high-volume, quaternary soft-tissue sarcoma centre to identify patients with histopathologically confirmed extramedullary plasmacytoma affecting the gastrointestinal tract. Results Gastrointestinal extramedullary plasmacytomas can present with mass effect or organ-specific dysfunction. Techniques for tissue diagnosis of extramedullary plasmacytoma vary dependent on location, with a formal diagnosis often being made from a resected specimen. Management can include surgery, radiotherapy, systemic chemotherapy or a combination. No high-quality evidence base exists to guide treatment. Two case studies of operated gastrointestinal extramedullary plasmacytoma are presented at different phases of disease progression, with a resultant impact on survival. Conclusion Intra-abdominal extramedullary plasmacytoma is a rare and heterogeneous condition that lacks consensus guidelines for diagnosis and management. Collaboration between international specialist centres will create better quality evidence for treatment of this cohort.

Indexed as

AgedCombined Modality TherapyDisease ProgressionFatal OutcomeFemaleGastrointestinal NeoplasmsHumansMalePlasmacytomaAbdominalMultiple myelomaPlasmacytomaSurgery

Identifiers

PMID29692194
PMCPMC5956591

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.