Evidence map›Paper›PMID 29691700›Full record

ArticleAmino acids2018

PET imaging of Hsp90 expression in pancreatic cancer using a new

Xiaohui Wang, Jun Zhang, Hubing Wu, Yumin Li, Peter S Conti, Kai Chen

Open access · greenAbstract read
In one paragraph

Article in Amino acids, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. [EJNMMI radiopharmacy and chemistry · 2025
    Article
  3. Review
  4. Radiosynthesis and Evaluation of [Journal of labelled compounds & radiopharmaceuticals · 2025
    Article
  5. Review
  6. Review
  7. Antimicrobial peptides as potential therapy for gastrointestinal cancers.Naunyn-Schmiedeberg's archives of pharmacology · 2023
    Review
  8. Journal of Cancer · 2022
    Article
  9. Review
  10. Evaluation of [Theranostics · 2019
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Xiaohui WangDepartment of Nuclear Medicine, Lanzhou University Second Hospital, Lanzhou, 730000, Gansu, China.
Jun ZhangDepartment of Radiology, Molecular Imaging Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.
Hubing WuDepartment of Radiology, Molecular Imaging Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.
Yumin LiKey Laboratory of Digestive System Tumors of Gansu Province, Lanzhou University Second Hospital, Lanzhou, 730000, Gansu, China. liym@lzu.edu.cn.
Peter S ContiDepartment of Radiology, Molecular Imaging Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.
Kai ChenDepartment of Radiology, Molecular Imaging Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA. chenkai@med.usc.edu.ORCID http://orcid.org/0000-0002-8647-1182
University of Southern California · USLanzhou University Second Hospital · CN

Funding

USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Fumito Ito · 1985 to 2026
$181.4M
International S&T Cooperation Program of China 2015DFA31650NCI NIH HHS P30 CA014089
6 · The paper itself

Abstract

Heat shock protein 90 (Hsp90) plays a vital role in the progress of malignant disease and elevated Hsp90 expression has been reported in pancreatic cancer. In this study, we radiolabeled a dimeric Sansalvamide A derivative (Di-San A1) with

Indexed as

Gene Expression Regulation, NeoplasticPancreatic NeoplasmsPositron-Emission TomographyAnimalsCell Line, TumorCopperDepsipeptidesFemaleHeterograftsHSP90 Heat-Shock ProteinsHumansMiceMice, NudeNeoplasm ProteinsNeoplasm TransplantationProtein MultimerizationCopperDepsipeptidesHSP90 Heat-Shock ProteinsNeoplasm Proteinssansalvamide A64Cu labelingDimeric Sansalvamide A decapeptideHsp90Pancreatic cancerPET imaging

Identifiers

PMID29691700
PMCPMC7457833
OpenAlexW2800224370

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.