Evidence map›Paper›PMID 29691693›Full record

ArticleFish physiology and biochemistry2018

Environmentally relevant concentrations of mercury exposure alter thyroid hormone levels and gene expression in the hypothalamic-pituitary-thyroid axis of zebrafish larvae.

Yaling Sun, Yingwen Li, Zhihao Liu, Qiliang Chen

Abstract read
PubMed Publisher
In one paragraph

Article in Fish physiology and biochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
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  8. Review
  9. Article
  10. Association of exposure to multiple metals with papillary thyroid cancer risk in China.Environmental science and pollution research international · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yaling SunChongqing Key Laboratory of Animal Biology, School of Life Sciences, Chongqing Normal University, Chongqing, 401331, China.
Yingwen LiChongqing Key Laboratory of Animal Biology, School of Life Sciences, Chongqing Normal University, Chongqing, 401331, China.
Zhihao LiuChongqing Key Laboratory of Animal Biology, School of Life Sciences, Chongqing Normal University, Chongqing, 401331, China.
Qiliang ChenChongqing Key Laboratory of Animal Biology, School of Life Sciences, Chongqing Normal University, Chongqing, 401331, China. xncql@126.com.ORCID http://orcid.org/0000-0001-8584-7806
Chongqing Normal University · CN

Funding

Postgraduate Research Innovation Project of Chongqing Normal University YKC17009the Chongqing Research Program of Basic Research and Frontier Technology cstc2015jcyjA80012the Foundation Project of Chongqing Normal University 15XLB012the Scientific and Technological Research Program of Chongqing Municipal Education Commission KJ1500331
6 · The paper itself

Abstract

Mercury (Hg) is one of the most toxic heavy metals that can cause severe damage to fish. Studies have demonstrated that Hg has a specific affinity for the endocrine system, but little is known about the effects of Hg on thyroid endocrine system in fish. In this study, zebrafish embryos were exposed to environmentally relevant concentrations of 1, 4, and 16 μg/L Hg

Indexed as

AnimalsEnvironmental PollutantsGene Expression Regulation, DevelopmentalHypothalamusLarvaMercuryPituitary GlandThyroid GlandThyroid HormonesZebrafishEnvironmental PollutantsMercuryThyroid HormonesHypothalamic–pituitary–thyroid axisMercury exposureThyroid endocrine systemThyroid hormones

Identifiers

PMID29691693
OpenAlexW2801487844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.