Evidence map›Paper›PMID 29691484›Full record

ArticleThe Journal of antibiotics2018

Hamuramicins A and B, 22-membered macrolides, produced by an endophytic actinomycete Allostreptomyces sp. K12-0794.

Takuya Suga, Tōru Kimura, Yuki Inahashi, Masato Iwatsuki, Kenichi Nonaka, Akira Také, Atsuko Matsumoto, Yōko Takahashi, Satoshi Ōmura, Takuji Nakashima

Abstract read
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In one paragraph

Article in The Journal of antibiotics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Draft Genome Sequence ofMicrobiology resource announcements · 2022
    Article
  4. A review of approaches to control bacterial leaf blight in rice.World journal of microbiology & biotechnology · 2022
    Review
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Takuya SugaKitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Tokyo, 108-8641, Japan. di13003@st.kitasato-u.ac.jp.
Tōru KimuraGraduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Tokyo, 108-8641, Japan.
Yuki InahashiKitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Tokyo, 108-8641, Japan.
Masato IwatsukiKitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Tokyo, 108-8641, Japan.
Kenichi NonakaKitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Tokyo, 108-8641, Japan.
Akira TakéKitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Tokyo, 108-8641, Japan.
Atsuko MatsumotoKitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Tokyo, 108-8641, Japan.
Yōko TakahashiKitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Tokyo, 108-8641, Japan.
Satoshi ŌmuraKitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Tokyo, 108-8641, Japan.
Takuji NakashimaKitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Tokyo, 108-8641, Japan. takuji@lisci.kitasato-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two new compounds, designated as hamuramicins A (1) and B (2), were isolated from the cultured broth of an endophytic actinomycete Allostreptomyces sp. K12-0794 by silica gel column chromatography and HPLC. The structures of 1 and 2 were elucidated as 22-membered macrolide containing triene and trienone with an alkyl side chain by spectroscopic analyses including NMR experiments. Both compounds showed growth inhibition activity against Kocuria rhizophia and Xanthomonas oryzae pv. oryzae as well as human cell line toxicity.

Indexed as

ActinomycetaceaeAnti-Bacterial AgentsAntibiotics, AntineoplasticBacteriaCell Line, TumorChromatography, High Pressure LiquidEndophytesFermentationHumansMacrolidesMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsAnti-Bacterial AgentsAntibiotics, AntineoplasticMacrolides

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.