ArticleScientific reports2018
Molecular basis of autotrophic vs mixotrophic growth in Chlorella sorokiniana.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 145 citations in OpenAlex.
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- The Effects of Dietary Protein Level on the Growth Performance, Body Composition, Intestinal Digestion and Microbiota ofAnimals : an open access journal from MDPI · 2023Article
- Transcriptomic and metabolomic analyses revealed regulation mechanism of mixotrophic Cylindrotheca sp. glycerol utilization and biomass promotion.Biotechnology for biofuels and bioproducts · 2023Article
- Cellular response ofFrontiers in plant science · 2023Article
- Metabolic and Proteomic Analysis ofMolecules (Basel, Switzerland) · 2022Article
- A Water Extract fromNutrients · 2022Article
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- Photosynthesis and pigment production: elucidation of the interactive effects of nutrients and light on Chlamydomonas reinhardtii.Bioprocess and biosystems engineering · 2022Article
- Reducing culture medium nitrogen supply coupled with replenishing carbon nutrient simultaneously enhances the biomass and lipid production ofFrontiers in microbiology · 2022Article
- Metabolism ofFrontiers in plant science · 2022Article
- Enhanced β-carotene and Biomass Production by Induced Mixotrophy inMetabolites · 2021Article
- Trophic state alters the mechanism whereby energetic coupling between photosynthesis and respiration occurs in Euglena gracilis.The New phytologist · 2021Article
- COPlant, cell & environment · 2021Article
- Mixotrophic growth of the extremophile Galdieria sulphuraria reveals the flexibility of its carbon assimilation metabolism.The New phytologist · 2021Article
- Transcriptome and Metabolome Profiling of a Novel IsolateFrontiers in microbiology · 2021Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
In this work, we investigated the molecular basis of autotrophic vs. mixotrophic growth of Chlorella sorokiniana, one of the most productive microalgae species with high potential to produce biofuels, food and high value compounds. To increase biomass accumulation, photosynthetic microalgae are commonly cultivated in mixotrophic conditions, adding reduced carbon sources to the growth media. In the case of C. sorokiniana, the presence of acetate enhanced biomass, proteins, lipids and starch productivity when compared to autotrophic conditions. Despite decreased chlorophyll content, photosynthetic properties were essentially unaffected while differential gene expression profile revealed transcriptional regulation of several genes mainly involved in control of carbon flux. Interestingly, acetate assimilation caused upregulation of phosphoenolpyruvate carboxylase enzyme, enabling potential recovery of carbon atoms lost by acetate oxidation. The obtained results allowed to associate the increased productivity observed in mixotrophy in C. sorokiniana with a different gene regulation leading to a fine regulation of cell metabolism.
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